Identity
HGNC
LOCATION
12q13.11
LOCUSID
ALIAS
Tah1,hSpagh
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79657
MIM: 611477
HGNC: 26151
Ensembl: ENSG00000005175
Variants:
dbSNP: 79657
ClinVar: 79657
TCGA: ENSG00000005175
COSMIC: RPAP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000005175 | ENST00000005386 | Q9H6T3 |
| ENSG00000005175 | ENST00000380650 | Q9H6T3 |
| ENSG00000005175 | ENST00000432584 | Q9H6T3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29662061 | 2018 | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. | 30 |
| 30033218 | 2018 | Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. | 20 |
| 29662061 | 2018 | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. | 30 |
| 30033218 | 2018 | Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. | 20 |
| 23159623 | 2013 | RPAP3 splicing variant isoform 1 interacts with PIH1D1 to compose R2TP complex for cell survival. | 9 |
| 23159623 | 2013 | RPAP3 splicing variant isoform 1 interacts with PIH1D1 to compose R2TP complex for cell survival. | 9 |
| 21184742 | 2011 | RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway. | 2 |
| 21184742 | 2011 | RPAP3 enhances cytotoxicity of doxorubicin by impairing NF-kappa B pathway. | 2 |
| 20864038 | 2010 | HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II. | 141 |
| 20864038 | 2010 | HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II. | 141 |
| 19180575 | 2009 | RPAP3 interacts with Reptin to regulate UV-induced phosphorylation of H2AX and DNA damage. | 9 |
| 19450687 | 2009 | High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes. | 47 |
| 19180575 | 2009 | RPAP3 interacts with Reptin to regulate UV-induced phosphorylation of H2AX and DNA damage. | 9 |
| 19450687 | 2009 | High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes. | 47 |
| 18538670 | 2008 | Molecular cloning of novel Monad binding protein containing tetratricopeptide repeat domains. | 19 |
Citation
Dessen P
RPAP3 (RNA polymerase II associated protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2011-03-01
Online version: http://atlasgeneticsoncology.org/gene/52136/rpap3
