RCN1 (reticulocalbin 1)

2011-04-01  

Identity

HGNC
RCN1
LOCATION
11p13
LOCUSID
5954
ALIAS
HEL-S-84,PIG20,RCAL,RCN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5954
MIM: 602735
HGNC: 9934
Ensembl: ENSG00000049449

Variants:

dbSNP: 5954
ClinVar: 5954
TCGA: ENSG00000049449
COSMIC: RCN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000049449ENST00000054950Q15293
ENSG00000049449ENST00000054950V9HW95
ENSG00000049449ENST00000527337H0YER5
ENSG00000049449ENST00000528630H0YDA4
ENSG00000049449ENST00000532721E9PLM2

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387137382024Downregulation of RCN1 inhibits esophageal squamous cell carcinoma progression and M2 macrophage polarization.0
387137382024Downregulation of RCN1 inhibits esophageal squamous cell carcinoma progression and M2 macrophage polarization.0
377467422023Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells.0
380574062023RCN1 deficiency inhibits oral squamous cell carcinoma progression and THP-1 macrophage M2 polarization.1
377467422023Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells.0
380574062023RCN1 deficiency inhibits oral squamous cell carcinoma progression and THP-1 macrophage M2 polarization.1
324367702020Reticulocalbin-1 knockdown increases the sensitivity of cells to Adriamycin in nasopharyngeal carcinoma and promotes endoplasmic reticulum stress-induced cell apoptosis.12
328717602020Salivary NUS1 and RCN1 Levels as Biomarkers for Oral Squamous Cell Carcinoma Diagnosis.11
324367702020Reticulocalbin-1 knockdown increases the sensitivity of cells to Adriamycin in nasopharyngeal carcinoma and promotes endoplasmic reticulum stress-induced cell apoptosis.12
328717602020Salivary NUS1 and RCN1 Levels as Biomarkers for Oral Squamous Cell Carcinoma Diagnosis.11
301729152019Overexpression of RCN1 correlates with poor prognosis and progression in non-small cell lung cancer.17
301729152019Overexpression of RCN1 correlates with poor prognosis and progression in non-small cell lung cancer.17
294539002018Downregulation of reticulocalbin-1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells.21
294539002018Downregulation of reticulocalbin-1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells.21
274685732016Circulating Reticulocalbin 1 and Reticulocalbin 3 in Systemic Sclerosis Patients: Results of a Case Control Study.1

Citation

Dessen P

RCN1 (reticulocalbin 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52179