GP2 (glycoprotein 2)

2011-04-01  

Identity

HGNC
LOCATION
16p12.3
LOCUSID
ALIAS
ZAP75

Other Information

Locus ID:

NCBI: 2813
MIM: 602977
HGNC: 4441
Ensembl: ENSG00000169347

Variants:

dbSNP: 2813
ClinVar: 2813
TCGA: ENSG00000169347
COSMIC: GP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169347ENST00000302555P55259
ENSG00000169347ENST00000341642P55259
ENSG00000169347ENST00000381360P55259
ENSG00000169347ENST00000381362P55259
ENSG00000169347ENST00000572347I3L4Y3
ENSG00000169347ENST00000572478I3L486
ENSG00000169347ENST00000574982I3L324
ENSG00000169347ENST00000575449I3L2Z7
ENSG00000169347ENST00000575582I3L3I2

Expression (GTEx)

0
5000
10000
15000

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
352733902022Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.7
352733902022Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.7
328863112021Antibodies Against Glycoprotein 2 Are Specific Biomarkers for Pediatric Crohn's Disease.2
343268132021Common Variants in NUS1 and GP2 Genes Contributed to the Risk of Gestational Diabetes Mellitus.4
328863112021Antibodies Against Glycoprotein 2 Are Specific Biomarkers for Pediatric Crohn's Disease.2
343268132021Common Variants in NUS1 and GP2 Genes Contributed to the Risk of Gestational Diabetes Mellitus.4
325812502020Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.25
325812502020Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.25
302335742018Mucosal Autoimmunity to Cell-Bound GP2 Isoforms Is a Sensitive Marker in PSC and Associated With the Clinical Phenotype.6
304113912018Loss of tolerance to glycoprotein 2 isoforms 1 and 4 is associated with Crohn's disease of the pouch.3
302335742018Mucosal Autoimmunity to Cell-Bound GP2 Isoforms Is a Sensitive Marker in PSC and Associated With the Clinical Phenotype.6
304113912018Loss of tolerance to glycoprotein 2 isoforms 1 and 4 is associated with Crohn's disease of the pouch.3
288357092017Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.67
288357092017Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.67
259685832015Rediscovery of the Anti-Pancreatic Antibodies and Evaluation of their Prognostic Value in a Prospective Clinical Cohort of Crohn's Patients: The Importance of Specific Target Antigens [GP2 and CUZD1].24

Citation

Dessen P

GP2 (glycoprotein 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52181/gp2