SHOX2 (short stature homeobox 2)

2011-04-01  

Identity

HGNC
SHOX2
LOCATION
3q25.32
LOCUSID
6474
ALIAS
OG12,OG12X,SHOT

Other Information

Locus ID:

NCBI: 6474
MIM: 602504
HGNC: 10854
Ensembl: ENSG00000168779

Variants:

dbSNP: 6474
ClinVar: 6474
TCGA: ENSG00000168779
COSMIC: SHOX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168779ENST00000389589O60902
ENSG00000168779ENST00000425436A6NLG4
ENSG00000168779ENST00000441443O60902
ENSG00000168779ENST00000483851O60902
ENSG00000168779ENST00000554685A0A087WVB7

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
388400772024Association of the SHOX2 and RASSF1A methylation levels with the pathological evolution of early-stage lung adenocarcinoma.0
388400772024Association of the SHOX2 and RASSF1A methylation levels with the pathological evolution of early-stage lung adenocarcinoma.0
326838472022lncRNA SNHG11 promotes the development of colorectal cancer by mediating miR-339-3p/SHOX2.2
350883782022SHOX2 methylation in Vietnamese patients with lung cancer.3
326838472022lncRNA SNHG11 promotes the development of colorectal cancer by mediating miR-339-3p/SHOX2.2
350883782022SHOX2 methylation in Vietnamese patients with lung cancer.3
342755162021[Diagnostic Efficacy of SHOX2 Gene Hypermethylation for Lung Cancer: A Meta-Analysis].0
343088482021[SHOX2 promotes migration, invasion and stemness of bladder cancer cells in vitro].1
344653612021SHOX2 cooperates with STAT3 to promote breast cancer metastasis through the transcriptional activation of WASF3.12
342755162021[Diagnostic Efficacy of SHOX2 Gene Hypermethylation for Lung Cancer: A Meta-Analysis].0
343088482021[SHOX2 promotes migration, invasion and stemness of bladder cancer cells in vitro].1
344653612021SHOX2 cooperates with STAT3 to promote breast cancer metastasis through the transcriptional activation of WASF3.12
311835902020IGF2-AS affects the prognosis and metastasis of gastric adenocarcinoma via acting as a ceRNA of miR-503 to regulate SHOX2.22
322665382020Signaling pathways and clinical application of RASSF1A and SHOX2 in lung cancer.15
331677122020A Novel Diagnosis Method Based on Methylation Analysis of SHOX2 and Serum Biomarker for Early Stage Lung Cancer.6

Citation

Dessen P

SHOX2 (short stature homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52186/teaching-explorer/gene-fusions-explorer/