Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
AICL,CLECSF2,HP10085,IFNRG1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9976
MIM: 603242
HGNC: 2053
Ensembl: ENSG00000110852
Variants:
dbSNP: 9976
ClinVar: 9976
TCGA: ENSG00000110852
COSMIC: CLEC2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110852 | ENST00000228438 | Q92478 |
| ENSG00000110852 | ENST00000538152 | F5H631 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35902826 | 2022 | Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study. | 0 |
| 35902826 | 2022 | Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study. | 0 |
| 31280468 | 2020 | Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease. | 11 |
| 31280468 | 2020 | Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease. | 11 |
| 29980609 | 2018 | Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80. | 4 |
| 29980609 | 2018 | Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80. | 4 |
| 27960039 | 2017 | Physiologic and pathophysiologic roles of interaction between C-type lectin-like receptor 2 and podoplanin: partners from in utero to adulthood. | 32 |
| 27960039 | 2017 | Physiologic and pathophysiologic roles of interaction between C-type lectin-like receptor 2 and podoplanin: partners from in utero to adulthood. | 32 |
| 25462818 | 2015 | C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets. | 3 |
| 26418160 | 2015 | Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis. | 25 |
| 25462818 | 2015 | C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets. | 3 |
| 26418160 | 2015 | Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis. | 25 |
| 23929856 | 2013 | Genetically coupled receptor-ligand pair NKp80-AICL enables autonomous control of human NK cell responses. | 22 |
| 23929856 | 2013 | Genetically coupled receptor-ligand pair NKp80-AICL enables autonomous control of human NK cell responses. | 22 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
Citation
Dessen P
CLEC2B (C-type lectin domain family 2 member B)
Atlas Genet Cytogenet Oncol Haematol. 2011-04-01
Online version: http://atlasgeneticsoncology.org/gene/52189/clec2b
