FCGR2C (Fc fragment of IgG receptor IIc (gene/pseudogene))

2011-05-01  

Identity

HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
CD32,CD32C,CDW32,FCG2,FCRIIC,IGFR2

Other Information

Locus ID:

NCBI: 9103
MIM: 612169
HGNC: 15626

Variants:

dbSNP: 9103
ClinVar: 9103
COSMIC: FCGR2C

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
LeishmaniasisKEGGko05140
LeishmaniasisKEGGhsa05140
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Staphylococcus aureus infectionKEGGko05150
Staphylococcus aureus infectionKEGGhsa05150
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Fcgamma receptor (FCGR) dependent phagocytosisREACTOMER-HSA-2029480
FCGR activationREACTOMER-HSA-2029481
Regulation of actin dynamics for phagocytic cup formationREACTOMER-HSA-2029482
Role of phospholipids in phagocytosisREACTOMER-HSA-2029485
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
349170812021An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition.2
349170812021An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition.2
305639692019The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression.7
305639692019The FCGR2C allele that modulated the risk of HIV-1 infection in the Thai RV144 vaccine trial is implicated in HIV-1 disease progression.7
277427942017FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma.8
286055532017Pyruvate Kinase and Fcγ Receptor Gene Copy Numbers Associated With Malaria Phenotypes.5
288998542017Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease.12
277427942017FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma.8
286055532017Pyruvate Kinase and Fcγ Receptor Gene Copy Numbers Associated With Malaria Phenotypes.5
288998542017Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease.12
266739652016Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa.22
268011492016Polymorphism of FCGR2A, FCGR2C, and FCGR3B Genes in the Pathogenesis of Sarcoidosis.8
270152732016FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells.9
266739652016Variability at the FCGR locus: characterization in Black South Africans and evidence for ethnic variation in and out of Africa.22
268011492016Polymorphism of FCGR2A, FCGR2C, and FCGR3B Genes in the Pathogenesis of Sarcoidosis.8

Citation

Dessen P

FCGR2C (Fc fragment of IgG receptor IIc (gene/pseudogene))

Atlas Genet Cytogenet Oncol Haematol. 2011-05-01

Online version: http://atlasgeneticsoncology.org/gene/52219/fcgr2c