ACTR8 (actin related protein 8)

2011-06-01  

Identity

HGNC
ACTR8
LOCATION
3p21.1
LOCUSID
93973
ALIAS
ARP8,INO80N,hArp8
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 93973
HGNC: 14672
Ensembl: ENSG00000113812

Variants:

dbSNP: 93973
ClinVar: 93973
TCGA: ENSG00000113812
COSMIC: ACTR8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113812ENST00000335754Q9H981
ENSG00000113812ENST00000482349Q9H981
ENSG00000113812ENST00000486794H0Y849
ENSG00000113812ENST00000498740C9J7L6

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DNA RepairREACTOMER-HSA-73894
Nucleotide Excision RepairREACTOMER-HSA-5696398
Global Genome Nucleotide Excision Repair (GG-NER)REACTOMER-HSA-5696399
DNA Damage Recognition in GG-NERREACTOMER-HSA-5696394
DeubiquitinationREACTOMER-HSA-5688426
UCH proteinasesREACTOMER-HSA-5689603

References

Pubmed IDYearTitleCitations
252996022014DNA binding properties of the actin-related protein Arp8 and its role in DNA repair.10
252996022014DNA binding properties of the actin-related protein Arp8 and its role in DNA repair.10
229771802012Structure of Actin-related protein 8 and its contribution to nucleosome binding.30
229771802012Structure of Actin-related protein 8 and its contribution to nucleosome binding.30
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
209710672010The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner.30
209710672010The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner.30
181639882008The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment.17
181639882008The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment.17

Citation

Dessen P

ACTR8 (actin related protein 8)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52229/js/case-report-explorer/