Identity
HGNC
LOCATION
3q26.33
LOCUSID
ALIAS
ACTL6,ARPN-BETA,Arp4,BAF53A,INO80K
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 86
MIM: 604958
HGNC: 24124
Ensembl: ENSG00000136518
Variants:
dbSNP: 86
ClinVar: 86
TCGA: ENSG00000136518
COSMIC: ACTL6A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38523407 | 2024 | High expression of ACTL6A leads to poor prognosis of oral squamous cell carcinoma patients through promoting malignant progression. | 0 |
| 38523407 | 2024 | High expression of ACTL6A leads to poor prognosis of oral squamous cell carcinoma patients through promoting malignant progression. | 0 |
| 36631007 | 2023 | Targeting VPS72 inhibits ACTL6A/MYC axis activity in HCC progression. | 3 |
| 36768349 | 2023 | Actin-like Protein 6A Expression Correlates with Cancer Stem Cell-like Features and Poor Prognosis in Ovarian Cancer. | 4 |
| 36631007 | 2023 | Targeting VPS72 inhibits ACTL6A/MYC axis activity in HCC progression. | 3 |
| 36768349 | 2023 | Actin-like Protein 6A Expression Correlates with Cancer Stem Cell-like Features and Poor Prognosis in Ovarian Cancer. | 4 |
| 34898277 | 2022 | DNA Damage Triggers the Nuclear Accumulation of RASSF6 Tumor Suppressor Protein via CDK9 and BAF53 To Regulate p53 Target Gene Transcription. | 0 |
| 35182941 | 2022 | ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells. | 2 |
| 36526622 | 2022 | BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation. | 4 |
| 34898277 | 2022 | DNA Damage Triggers the Nuclear Accumulation of RASSF6 Tumor Suppressor Protein via CDK9 and BAF53 To Regulate p53 Target Gene Transcription. | 0 |
| 35182941 | 2022 | ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells. | 2 |
| 36526622 | 2022 | BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation. | 4 |
| 33408251 | 2021 | ACTL6A promotes repair of cisplatin-induced DNA damage, a new mechanism of platinum resistance in cancer. | 28 |
| 33896314 | 2021 | ACTL6A promotes the growth in non-small cell lung cancer by regulating Hippo/Yap pathway. | 2 |
| 34687603 | 2021 | Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma. | 14 |
Citation
Dessen P
ACTL6A (actin like 6A)
Atlas Genet Cytogenet Oncol Haematol. 2011-06-01
Online version: http://atlasgeneticsoncology.org/gene/52255/actl6a
