Identity
HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
CGD3,NCF,P40PHOX,SH3PXD4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4689
MIM: 601488
HGNC: 7662
Ensembl: ENSG00000100365
Variants:
dbSNP: 4689
ClinVar: 4689
TCGA: ENSG00000100365
COSMIC: NCF4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444760 | Leukemia, Myeloid, Acute | Disease | ClinicalAnnotation | associated | PD | 28485375 | |
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | 16330681, 19448608, 26799497, 28485375, 28763429 | |
| PA446108 | Colorectal Neoplasms | Disease | VariantAnnotation | not associated | PD | ||
| PA448497 | aspirin | Chemical | VariantAnnotation | not associated | PD | ||
| PA449412 | doxorubicin | Chemical | ClinicalAnnotation, Pathway | associated | PD | 16330681, 19448608, 21048526, 26799497, 28485375, 28763429 | |
| PA449961 | idarubicin | Chemical | ClinicalAnnotation | associated | PD | 16330681, 19448608, 26799497, 28485375, 28763429 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38886341 | 2024 | NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance. | 0 |
| 38886341 | 2024 | NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance. | 0 |
| 38085396 | 2023 | Polymorphisms of the NCF4 Gene Increase the Risk of Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus. | 0 |
| 38085396 | 2023 | Polymorphisms of the NCF4 Gene Increase the Risk of Chronic Heart Failure in Patients with Type 2 Diabetes Mellitus. | 0 |
| 34708124 | 2021 | NCF1/2/4 Are Prognostic Biomarkers Related to the Immune Infiltration of Kidney Renal Clear Cell Carcinoma. | 10 |
| 34708124 | 2021 | NCF1/2/4 Are Prognostic Biomarkers Related to the Immune Infiltration of Kidney Renal Clear Cell Carcinoma. | 10 |
| 33145364 | 2020 | Association of NCF2, NCF4, and CYBA Gene Polymorphisms with Rheumatoid Arthritis in a Chinese Population. | 4 |
| 33145364 | 2020 | Association of NCF2, NCF4, and CYBA Gene Polymorphisms with Rheumatoid Arthritis in a Chinese Population. | 4 |
| 29311151 | 2018 | Tks adaptor proteins at a glance. | 22 |
| 29969437 | 2018 | Inherited p40phox deficiency differs from classic chronic granulomatous disease. | 43 |
| 29311151 | 2018 | Tks adaptor proteins at a glance. | 22 |
| 29969437 | 2018 | Inherited p40phox deficiency differs from classic chronic granulomatous disease. | 43 |
| 28096301 | 2017 | Phosphoinositol 3-phosphate acts as a timer for reactive oxygen species production in the phagosome. | 7 |
| 28096301 | 2017 | Phosphoinositol 3-phosphate acts as a timer for reactive oxygen species production in the phagosome. | 7 |
| 26289093 | 2015 | Association between NCF4 rs4821544T/C polymorphism and inflammatory bowel disease risk in Caucasian: a meta-analysis. | 4 |
Citation
Dessen P
NCF4 (neutrophil cytosolic factor 4)
Atlas Genet Cytogenet Oncol Haematol. 2011-08-01
Online version: http://atlasgeneticsoncology.org/gene/52301/ncf4
