Identity
HGNC
LOCATION
20q11.21
LOCUSID
ALIAS
C20orf114,LPLUNC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 92747
HGNC: 16108
Ensembl: ENSG00000125999
Variants:
dbSNP: 92747
ClinVar: 92747
TCGA: ENSG00000125999
COSMIC: BPIFB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125999 | ENST00000253354 | Q8TDL5 |
| ENSG00000125999 | ENST00000423645 | A2A2R0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Antimicrobial peptides | REACTOME | R-HSA-6803157 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37847709 | 2023 | BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance. | 0 |
| 37847709 | 2023 | BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance. | 0 |
| 30886235 | 2019 | LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma. | 25 |
| 30886235 | 2019 | LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma. | 25 |
| 29123267 | 2018 | BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM. | 53 |
| 29296079 | 2018 | Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD. | 16 |
| 29568064 | 2018 | BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression. | 44 |
| 29123267 | 2018 | BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM. | 53 |
| 29296079 | 2018 | Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD. | 16 |
| 29568064 | 2018 | BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression. | 44 |
| 25574903 | 2015 | Polymorphisms associated with expression of BPIFA1/BPIFB1 and lung disease severity in cystic fibrosis. | 15 |
| 25979078 | 2015 | Elevated sputum BPIFB1 levels in smokers with chronic obstructive pulmonary disease: a longitudinal study. | 15 |
| 25574903 | 2015 | Polymorphisms associated with expression of BPIFA1/BPIFB1 and lung disease severity in cystic fibrosis. | 15 |
| 25979078 | 2015 | Elevated sputum BPIFB1 levels in smokers with chronic obstructive pulmonary disease: a longitudinal study. | 15 |
| 23708661 | 2014 | LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation. | 74 |
Citation
Dessen P
BPIFB1 (BPI fold containing family B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-08-01
Online version: http://atlasgeneticsoncology.org/gene/52308/bpifb1
