Identity
HGNC
LOCATION
15q26.3
LOCUSID
ALIAS
CHSY,CSS1,ChSy-1,TPBS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22856
MIM: 608183
HGNC: 17198
Ensembl: ENSG00000131873
Variants:
dbSNP: 22856
ClinVar: 22856
TCGA: ENSG00000131873
COSMIC: CHSY1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131873 | ENST00000254190 | Q86X52 |
| ENSG00000131873 | ENST00000543813 | A0A2R8Y7B7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34716872 | 2022 | LncRNA LINC01094 contributes to glioma progression by modulating miR-224-5p/CHSY1 axis. | 6 |
| 34716872 | 2022 | LncRNA LINC01094 contributes to glioma progression by modulating miR-224-5p/CHSY1 axis. | 6 |
| 34412565 | 2021 | CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration. | 3 |
| 34412565 | 2021 | CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration. | 3 |
| 28652022 | 2017 | CHSY1 promotes aggressive phenotypes of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. | 32 |
| 28652022 | 2017 | CHSY1 promotes aggressive phenotypes of hepatocellular carcinoma cells via activation of the hedgehog signaling pathway. | 32 |
| 26997434 | 2016 | Chondroitin sulfate synthase 1 expression is associated with malignant potential of soft tissue sarcomas with myxoid substance. | 11 |
| 26997434 | 2016 | Chondroitin sulfate synthase 1 expression is associated with malignant potential of soft tissue sarcomas with myxoid substance. | 11 |
| 24269551 | 2014 | A novel CHSY1 gene mutation underlies Temtamy preaxial brachydactyly syndrome in a Pakistani family. | 5 |
| 24269551 | 2014 | A novel CHSY1 gene mutation underlies Temtamy preaxial brachydactyly syndrome in a Pakistani family. | 5 |
| 23811343 | 2013 | A chondroitin synthase-1 (ChSy-1) missense mutation in a patient with neuropathy impairs the elongation of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1. | 5 |
| 23811343 | 2013 | A chondroitin synthase-1 (ChSy-1) missense mutation in a patient with neuropathy impairs the elongation of chondroitin sulfate chains initiated by chondroitin N-acetylgalactosaminyltransferase-1. | 5 |
| 21468578 | 2011 | Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer. | 19 |
| 21468578 | 2011 | Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer. | 19 |
| 21129727 | 2010 | Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signaling. | 40 |
Citation
Dessen P
CHSY1 (chondroitin sulfate synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-08-01
Online version: http://atlasgeneticsoncology.org/gene/52320/chsy1
