FASTKD2 (FAST kinase domains 2)

2011-08-01  

Identity

HGNC
LOCATION
2q33.3
LOCUSID
ALIAS
COXPD44,KIAA0971
FUSION GENES

Other Information

Locus ID:

NCBI: 22868
MIM: 612322
HGNC: 29160
Ensembl: ENSG00000118246

Variants:

dbSNP: 22868
ClinVar: 22868
TCGA: ENSG00000118246
COSMIC: FASTKD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118246ENST00000236980Q9NYY8
ENSG00000118246ENST00000236980A0A024R419
ENSG00000118246ENST00000402774Q9NYY8
ENSG00000118246ENST00000402774A0A024R419
ENSG00000118246ENST00000403094Q9NYY8
ENSG00000118246ENST00000403094A0A024R419
ENSG00000118246ENST00000418289C9JPI6

Expression (GTEx)

0
5
10
15
20
25
30
35
40

References

Pubmed IDYearTitleCitations
357293272022A novel homozygous missense mutation in the FASTKD2 gene leads to Lennox-Gastaut syndrome.1
357293272022A novel homozygous missense mutation in the FASTKD2 gene leads to Lennox-Gastaut syndrome.1
316920632020FASTKD2 promotes cancer cell progression through upregulating Myc expression in pancreatic ductal adenocarcinoma.5
319444552020Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency.14
316920632020FASTKD2 promotes cancer cell progression through upregulating Myc expression in pancreatic ductal adenocarcinoma.5
319444552020Mutations in FASTKD2 are associated with mitochondrial disease with multi-OXPHOS deficiency.14
290363962017The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.41
290363962017The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.41
253853692015FASTKD2 is associated with memory and hippocampal structure in older adults.27
263705832015FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation.51
253853692015FASTKD2 is associated with memory and hippocampal structure in older adults.27
263705832015FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation.51
254097622014Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain.11
254097622014Fas Activated Serine-Threonine Kinase Domains 2 (FASTKD2) mediates apoptosis of breast and prostate cancer cells through its novel FAST2 domain.11
214447242011A novel transcription complex that selectively modulates apoptosis of breast cancer cells through regulation of FASTKD2.39

Citation

Dessen P

FASTKD2 (FAST kinase domains 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52337/favicon/cancer-prone-explorer/