RGMB (repulsive guidance molecule BMP co-receptor b)

2011-09-01  

Identity

HGNC
RGMB
LOCATION
5q15
LOCUSID
285704
ALIAS
DRAGON
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 285704
MIM: 612687
HGNC: 26896
Ensembl: ENSG00000174136

Variants:

dbSNP: 285704
ClinVar: 285704
TCGA: ENSG00000174136
COSMIC: RGMB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174136ENST00000308234J3KNF6
ENSG00000174136ENST00000513185Q6NW40

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Netrin-1 signalingREACTOMER-HSA-373752

References

Pubmed IDYearTitleCitations
361533212022RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival.3
361533212022RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival.3
325766892020Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.13
325766892020Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.13
310613922019RGMB enhances the suppressive activity of the monomeric secreted form of CTLA-4.10
310613922019RGMB enhances the suppressive activity of the monomeric secreted form of CTLA-4.10
269108892016Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer.12
269108892016Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer.12
260299982015Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth.14
260558772015Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer.11
260299982015Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth.14
260558772015Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer.11
249700502014Tumour angiogenesis and repulsive guidance molecule b: a role in HGF- and BMP-7-mediated angiogenesis.9
249700502014Tumour angiogenesis and repulsive guidance molecule b: a role in HGF- and BMP-7-mediated angiogenesis.9
237447772013Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub.39

Citation

Dessen P

RGMB (repulsive guidance molecule BMP co-receptor b)

Atlas Genet Cytogenet Oncol Haematol. 2011-09-01

Online version: http://atlasgeneticsoncology.org/gene/52385