Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3670
MIM: 600366
HGNC: 6132
Ensembl: ENSG00000016082
Variants:
dbSNP: 3670
ClinVar: 3670
TCGA: ENSG00000016082
COSMIC: ISL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000016082 | ENST00000230658 | P61371 |
| ENSG00000016082 | ENST00000511384 | D6RBJ1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA24684 | AKT1 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36758343 | 2023 | Isl1 promotes gene transcription through physical interaction with Set1/Mll complexes. | 1 |
| 36830727 | 2023 | Genetic Variants of ISL1 Gene Promoter Identified from Congenital Tetralogy of Fallot Patients Alter Cellular Function Forming Disease Basis. | 3 |
| 37782193 | 2023 | Human breast milk cells are positive for the pioneer transcription factor ISL1. | 0 |
| 37863045 | 2023 | The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5. | 0 |
| 36758343 | 2023 | Isl1 promotes gene transcription through physical interaction with Set1/Mll complexes. | 1 |
| 36830727 | 2023 | Genetic Variants of ISL1 Gene Promoter Identified from Congenital Tetralogy of Fallot Patients Alter Cellular Function Forming Disease Basis. | 3 |
| 37782193 | 2023 | Human breast milk cells are positive for the pioneer transcription factor ISL1. | 0 |
| 37863045 | 2023 | The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5. | 0 |
| 34997427 | 2022 | Investigation of promoter methylation patterns association with genes expression profile of ISL1, MGMT and DMNT3b in tissue of breast cancer patients. | 2 |
| 35403434 | 2022 | ISL1 Promotes Human Glioblastoma-Derived Stem Cells' Self-Renewal by Activation of Sonic Hedgehog/GLI1 Function. | 5 |
| 36170181 | 2022 | Identification and functional analysis of genetic variants of ISL1 gene promoter in human atrial septal defects. | 0 |
| 34997427 | 2022 | Investigation of promoter methylation patterns association with genes expression profile of ISL1, MGMT and DMNT3b in tissue of breast cancer patients. | 2 |
| 35403434 | 2022 | ISL1 Promotes Human Glioblastoma-Derived Stem Cells' Self-Renewal by Activation of Sonic Hedgehog/GLI1 Function. | 5 |
| 36170181 | 2022 | Identification and functional analysis of genetic variants of ISL1 gene promoter in human atrial septal defects. | 0 |
| 33476445 | 2021 | Association of ISL1 polymorphisms and eosinophilic levels among otitis media patients. | 1 |
Citation
Dessen P
ISL1 (ISL LIM homeobox 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52393/isl1
