CDHR5 (cadherin related family member 5)

2011-10-01  

Identity

HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
MLPCDH,MU-PCDH,MUCDHL,MUPCDH
FUSION GENES

Other Information

Locus ID:

NCBI: 53841
MIM: 606839
HGNC: 7521
Ensembl: ENSG00000099834

Variants:

dbSNP: 53841
ClinVar: 53841
TCGA: ENSG00000099834
COSMIC: CDHR5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099834ENST00000397542Q9HBB8
ENSG00000099834ENST00000526077E9PLX6
ENSG00000099834ENST00000531088E9PKR2
ENSG00000099834ENST00000531177E9PMY2
ENSG00000099834ENST00000534311E9PPW2
ENSG00000099834ENST00000674088Q9HBB8

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
331882952021The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms.2
348712942021Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.4
331882952021The atypical cadherin MUCDHL antagonizes colon cancer formation and inhibits oncogenic signaling through multiple mechanisms.2
348712942021Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.4
330257442020Up-regulation of CDHR5 expression promotes malignant phenotype of pancreatic ductal adenocarcinoma.3
330257442020Up-regulation of CDHR5 expression promotes malignant phenotype of pancreatic ductal adenocarcinoma.3
273108722016Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes.3
273108722016Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes.3
264634592015Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cyst growth in ADPKD.7
264634592015Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cyst growth in ADPKD.7
247254092014Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.91
247254092014Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.91
222024562012Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and β-catenin activity in colon cancer cells.24
222024562012Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and β-catenin activity in colon cancer cells.24
213154192011Down-regulation of μ-protocadherin expression is a common event in colorectal carcinogenesis.9

Citation

Dessen P

CDHR5 (cadherin related family member 5)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52395/cdhr5