Identity
HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
LIG-2,LIG2,UFS2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9860
MIM: 608869
HGNC: 20889
Ensembl: ENSG00000198799
Variants:
dbSNP: 9860
ClinVar: 9860
TCGA: ENSG00000198799
COSMIC: LRIG2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198799 | ENST00000361127 | O94898 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38191889 | 2024 | A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models. | 0 |
| 38191889 | 2024 | A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models. | 0 |
| 34839782 | 2022 | Prognostic significance of LRIG2 and LRIG3 proteins in urothelial bladder carcinoma. | 0 |
| 36183058 | 2022 | LRIG2 regulates cell proliferation, migration and apoptosis of osteosarcoma. | 1 |
| 34839782 | 2022 | Prognostic significance of LRIG2 and LRIG3 proteins in urothelial bladder carcinoma. | 0 |
| 36183058 | 2022 | LRIG2 regulates cell proliferation, migration and apoptosis of osteosarcoma. | 1 |
| 33469151 | 2021 | LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes. | 9 |
| 33469151 | 2021 | LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes. | 9 |
| 31988476 | 2020 | Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling. | 7 |
| 33187279 | 2020 | A SINE-VNTR-Alu in the LRIG2 Promoter Is Associated with Gene Expression at the Locus. | 6 |
| 31988476 | 2020 | Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling. | 7 |
| 33187279 | 2020 | A SINE-VNTR-Alu in the LRIG2 Promoter Is Associated with Gene Expression at the Locus. | 6 |
| 30879766 | 2019 | Long non-coding RNA LINC00461/miR-149-5p/LRIG2 axis regulates hepatocellular carcinoma progression. | 25 |
| 30885509 | 2019 | Lrig2 and Hpse2, mutated in urofacial syndrome, pattern nerves in the urinary bladder. | 13 |
| 31580518 | 2019 | The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis. | 5 |
Citation
Dessen P
LRIG2 (leucine rich repeats and immunoglobulin like domains 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52428/lrig2
