Identity
HGNC
LOCATION
2p11.2
LOCUSID
ALIAS
CGI-149,NEDF,VPS24
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51652
MIM: 610052
HGNC: 29865
Ensembl: ENSG00000115561
Variants:
dbSNP: 51652
ClinVar: 51652
TCGA: ENSG00000115561
COSMIC: CHMP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115561 | ENST00000263856 | Q9Y3E7 |
| ENSG00000115561 | ENST00000409225 | Q9Y3E7 |
| ENSG00000115561 | ENST00000409727 | Q9Y3E7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38038147 | 2024 | CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis. | 1 |
| 38038147 | 2024 | CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis. | 1 |
| 35710109 | 2023 | A homozygous variant in CHMP3 is associated with complex hereditary spastic paraplegia. | 1 |
| 35710109 | 2023 | A homozygous variant in CHMP3 is associated with complex hereditary spastic paraplegia. | 1 |
| 34597582 | 2021 | RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis. | 4 |
| 34597582 | 2021 | RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis. | 4 |
| 31541468 | 2020 | miR-122-5p promotes aggression and epithelial-mesenchymal transition in triple-negative breast cancer by suppressing charged multivesicular body protein 3 through mitogen-activated protein kinase signaling. | 26 |
| 31541468 | 2020 | miR-122-5p promotes aggression and epithelial-mesenchymal transition in triple-negative breast cancer by suppressing charged multivesicular body protein 3 through mitogen-activated protein kinase signaling. | 26 |
| 24440309 | 2014 | CK2 involvement in ESCRT-III complex phosphorylation. | 5 |
| 24440309 | 2014 | CK2 involvement in ESCRT-III complex phosphorylation. | 5 |
| 21827950 | 2011 | Structural basis for ESCRT-III CHMP3 recruitment of AMSH. | 26 |
| 21827950 | 2011 | Structural basis for ESCRT-III CHMP3 recruitment of AMSH. | 26 |
| 19525971 | 2009 | Structural basis for ESCRT-III protein autoinhibition. | 123 |
| 19525971 | 2009 | Structural basis for ESCRT-III protein autoinhibition. | 123 |
| 18687924 | 2008 | Helical structures of ESCRT-III are disassembled by VPS4. | 193 |
Citation
Dessen P
CHMP3 (charged multivesicular body protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52434/chmp3
