TRA2A (transformer 2 alpha homolog)

2011-10-01  

Identity

HGNC
TRA2A
LOCATION
7p15.3
LOCUSID
29896
ALIAS
AWMS1,HSU53209
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29896
MIM: 602718
HGNC: 16645
Ensembl: ENSG00000164548

Variants:

dbSNP: 29896
ClinVar: 29896
TCGA: ENSG00000164548
COSMIC: TRA2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164548ENST00000297071Q13595
ENSG00000164548ENST00000297071Q549U1
ENSG00000164548ENST00000392502Q13595
ENSG00000164548ENST00000448549F8WEH2
ENSG00000164548ENST00000538367Q13595
ENSG00000164548ENST00000621813Q13595

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
356350942022Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.2
356350942022Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.2
319121462020Integrative network analysis identifies cell-specific trans regulators of m6A.42
323727072020TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.14
319121462020Integrative network analysis identifies cell-specific trans regulators of m6A.42
323727072020TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.14
303678952018TRA2A promotes proliferation, migration, invasion and epithelial mesenchymal transition of glioma cells.14
303678952018TRA2A promotes proliferation, migration, invasion and epithelial mesenchymal transition of glioma cells.14
284166062017TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative Splicing.30
284166062017TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative Splicing.30
259703452015Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression.10
259703452015Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression.10
232558072013Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.23
232558072013Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.23
214475982011Expression of tumor-promoting Cyr61 is regulated by hTRA2-β1 and acidosis.9

Citation

Dessen P

TRA2A (transformer 2 alpha homolog)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52439/deep-insight-explorer/meetings/js/lib/jquery-3.5.1.min.js