MUC7 (mucin 7, secreted)

2011-10-01  

Identity

HGNC
MUC7
LOCATION
4q13.3
LOCUSID
4589
ALIAS
MG2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4589
MIM: 158375
HGNC: 7518
Ensembl: ENSG00000171195

Variants:

dbSNP: 4589
ClinVar: 4589
TCGA: ENSG00000171195
COSMIC: MUC7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171195ENST00000304887Q8TAX7
ENSG00000171195ENST00000413702Q8TAX7
ENSG00000171195ENST00000456088Q8TAX7
ENSG00000171195ENST00000505411D6RHX1

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
35000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-linked glycosylation of mucinsREACTOMER-HSA-913709
Termination of O-glycan biosynthesisREACTOMER-HSA-977068
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
Dectin-2 familyREACTOMER-HSA-5621480
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)REACTOMER-HSA-5083632
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)REACTOMER-HSA-5083625
Defective GALNT12 causes colorectal cancer 1 (CRCS1)REACTOMER-HSA-5083636

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376570562023Diagnostic accuracy of MUC7 expression for bladder cancer: A systematic review and meta-analysis.0
376570562023Diagnostic accuracy of MUC7 expression for bladder cancer: A systematic review and meta-analysis.0
348614622022Mucins 5b and 7 and secretory IgA in the oral acquired pellicle of children with caries and caries-free children.1
357821372022Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains.4
363445532022MUC7 VNTR polymorphism and association with bronchial asthma in Egyptian children.1
348614622022Mucins 5b and 7 and secretory IgA in the oral acquired pellicle of children with caries and caries-free children.1
357821372022Streptococcus oralis Employs Multiple Mechanisms of Salivary Mucin Binding That Differ Between Strains.4
363445532022MUC7 VNTR polymorphism and association with bronchial asthma in Egyptian children.1
331900612021The comparative inhibitory potency of salivary mucins against human immunodeficiency virus type 1.2
331900612021The comparative inhibitory potency of salivary mucins against human immunodeficiency virus type 1.2
307458042019MUC7 Level As A New Saliva Risk Factor For Dental Caries In Adult Patients.6
314140882019Reduced sialyl-Lewis(x) on salivary MUC7 from patients with burning mouth syndrome.2
307458042019MUC7 Level As A New Saliva Risk Factor For Dental Caries In Adult Patients.6
314140882019Reduced sialyl-Lewis(x) on salivary MUC7 from patients with burning mouth syndrome.2
272467552017Polymorphisms of interleukin-1β and MUC7 genes in burning mouth syndrome.1

Citation

Dessen P

MUC7 (mucin 7, secreted)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52448/gene-fusions-explorer/favicon/favicon-16x16.png