Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8843
MIM: 606039
HGNC: 16824
Ensembl: ENSG00000255398
Variants:
dbSNP: 8843
ClinVar: 8843
TCGA: ENSG00000255398
COSMIC: HCAR3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000255398 | ENST00000528880 | P49019 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38103827 | 2024 | GPCR Screening Reveals that the Metabolite Receptor HCAR3 Regulates Epithelial Proliferation, Migration, and Cellular Respiration. | 1 |
| 38103827 | 2024 | GPCR Screening Reveals that the Metabolite Receptor HCAR3 Regulates Epithelial Proliferation, Migration, and Cellular Respiration. | 1 |
| 34968686 | 2022 | Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells. | 10 |
| 34968686 | 2022 | Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells. | 10 |
| 34852802 | 2021 | Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases. | 2 |
| 34948292 | 2021 | Alterations in Kynurenine and NAD(+) Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets. | 15 |
| 34852802 | 2021 | Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases. | 2 |
| 34948292 | 2021 | Alterations in Kynurenine and NAD(+) Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets. | 15 |
| 32102673 | 2020 | Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84. | 9 |
| 32102673 | 2020 | Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84. | 9 |
| 26656756 | 2016 | The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells. | 3 |
| 26656756 | 2016 | The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells. | 3 |
| 25839160 | 2015 | Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism. | 28 |
| 25839160 | 2015 | Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism. | 28 |
| 22289163 | 2012 | Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways. | 13 |
Citation
Dessen P
HCAR3 (hydroxycarboxylic acid receptor 3)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52451/hcar3
