ATP10B (ATPase phospholipid transporting 10B (putative))

2011-10-01  

Identity

HGNC
ATP10B
LOCATION
5q34
LOCUSID
23120
ALIAS
ATPVB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23120
HGNC: 13543
Ensembl: ENSG00000118322

Variants:

dbSNP: 23120
ClinVar: 23120
TCGA: ENSG00000118322
COSMIC: ATP10B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118322ENST00000327245O94823
ENSG00000118322ENST00000520108Q2YDW8
ENSG00000118322ENST00000642502A0A2R8YDI5

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Ion transport by P-type ATPasesREACTOMER-HSA-936837

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380864472024The lipid flippase ATP10B enables cellular lipid uptake under stress conditions.0
387542202024Role of ATP10B in Parkinson disease in a cohort from southern Spain.0
380864472024The lipid flippase ATP10B enables cellular lipid uptake under stress conditions.0
387542202024Role of ATP10B in Parkinson disease in a cohort from southern Spain.0
340914112021Genetic analysis of ATP10B for Parkinson's disease in Japan.2
340914112021Genetic analysis of ATP10B for Parkinson's disease in Japan.2
321723432020Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.27
321723432020Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.27

Citation

Dessen P

ATP10B (ATPase phospholipid transporting 10B (putative))

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52459