Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26499
MIM: 608007
HGNC: 19238
Ensembl: ENSG00000100558
Variants:
dbSNP: 26499
ClinVar: 26499
TCGA: ENSG00000100558
COSMIC: PLEK2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37921560 | 2024 | PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma. | 1 |
| 37921560 | 2024 | PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma. | 1 |
| 36928924 | 2023 | Pleckstrin-2-promoted PPM1B degradation plays an important role in transforming growth factor-β-induced breast cancer cell invasion and metastasis. | 1 |
| 37591356 | 2023 | Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer. | 3 |
| 36928924 | 2023 | Pleckstrin-2-promoted PPM1B degradation plays an important role in transforming growth factor-β-induced breast cancer cell invasion and metastasis. | 1 |
| 37591356 | 2023 | Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer. | 3 |
| 35122599 | 2022 | PLEK2 promotes the proliferation and migration of non-small cell lung cancer cells in a BRD4-dependent manner. | 1 |
| 35809313 | 2022 | The correlation between miR -34a-3p, miR -31, PLEK2 and the occurrence, development and prognosis of colorectal cancer. | 2 |
| 36002342 | 2022 | PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop. | 8 |
| 35122599 | 2022 | PLEK2 promotes the proliferation and migration of non-small cell lung cancer cells in a BRD4-dependent manner. | 1 |
| 35809313 | 2022 | The correlation between miR -34a-3p, miR -31, PLEK2 and the occurrence, development and prognosis of colorectal cancer. | 2 |
| 36002342 | 2022 | PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop. | 8 |
| 34331382 | 2021 | Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis. | 9 |
| 34601488 | 2021 | TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2. | 9 |
| 34676872 | 2021 | Pleckstrin 2 is a potential drug target for colorectal carcinoma with activation of APC/β‑catenin. | 2 |
Citation
Dessen P
PLEK2 (pleckstrin 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-11-01
Online version: http://atlasgeneticsoncology.org/gene/52493/plek2
