Identity
HGNC
LOCATION
10q23.31
LOCUSID
ALIAS
C56,G10P1,IFI-56,IFI-56K,IFI56,IFIT-1,IFNAI1,ISG56,P56,RNM561
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3434
MIM: 147690
HGNC: 5407
Ensembl: ENSG00000185745
Variants:
dbSNP: 3434
ClinVar: 3434
TCGA: ENSG00000185745
COSMIC: IFIT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185745 | ENST00000371804 | P09914 |
| ENSG00000185745 | ENST00000546318 | P09914 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37496288 | 2023 | Lysyl oxidase-like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3. | 3 |
| 37817224 | 2023 | Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1. | 0 |
| 37496288 | 2023 | Lysyl oxidase-like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3. | 3 |
| 37817224 | 2023 | Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1. | 0 |
| 34763233 | 2021 | Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma. | 7 |
| 34763233 | 2021 | Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma. | 7 |
| 31444947 | 2020 | Intrahepatic immune changes after hepatitis c virus eradication by direct-acting antiviral therapy. | 9 |
| 31977029 | 2020 | Expression and Prognostic Value of IFIT1 and IFITM3 in Head and Neck Squamous Cell Carcinoma. | 11 |
| 32363951 | 2020 | ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells. | 4 |
| 32962861 | 2020 | Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies. | 1 |
| 31444947 | 2020 | Intrahepatic immune changes after hepatitis c virus eradication by direct-acting antiviral therapy. | 9 |
| 31977029 | 2020 | Expression and Prognostic Value of IFIT1 and IFITM3 in Head and Neck Squamous Cell Carcinoma. | 11 |
| 32363951 | 2020 | ISG56 is involved in CXCL10 expression induced by TLR3 signaling in BEAS-2B bronchial epithelial cells. | 4 |
| 32962861 | 2020 | Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies. | 1 |
| 30626937 | 2019 | IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling. | 43 |
Citation
Dessen P
IFIT1 (interferon induced protein with tetratricopeptide repeats 1)
Atlas Genet Cytogenet Oncol Haematol. 2011-11-01
Online version: http://atlasgeneticsoncology.org/gene/52498/ifit1
