Identity
HGNC
LOCATION
7q36.1
LOCUSID
ALIAS
ERP70,ERP72,ERp-72
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9601
HGNC: 30167
Ensembl: ENSG00000155660
Variants:
dbSNP: 9601
ClinVar: 9601
TCGA: ENSG00000155660
COSMIC: PDIA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000155660 | ENST00000286091 | A0A499FI48 |
| ENSG00000155660 | ENST00000413966 | C9JMN9 |
| ENSG00000155660 | ENST00000652332 | P13667 |
| ENSG00000155660 | ENST00000652332 | A0A090N8Y2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38167446 | 2024 | Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway. | 0 |
| 38612722 | 2024 | Protein Disulfide Isomerase 4 Is an Essential Regulator of Endothelial Function and Survival. | 1 |
| 38167446 | 2024 | Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway. | 0 |
| 38612722 | 2024 | Protein Disulfide Isomerase 4 Is an Essential Regulator of Endothelial Function and Survival. | 1 |
| 36562654 | 2023 | CircPDIA4 Induces Gastric Cancer Progression by Promoting ERK1/2 Activation and Enhancing Biogenesis of Oncogenic circRNAs. | 16 |
| 36906674 | 2023 | PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma. | 10 |
| 36997943 | 2023 | Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy. | 6 |
| 37720188 | 2023 | LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17. | 1 |
| 38140584 | 2023 | PDIA4 Is a Host Factor Important for Lymphocytic Choriomeningitis Virus Infection. | 0 |
| 36562654 | 2023 | CircPDIA4 Induces Gastric Cancer Progression by Promoting ERK1/2 Activation and Enhancing Biogenesis of Oncogenic circRNAs. | 16 |
| 36906674 | 2023 | PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma. | 10 |
| 36997943 | 2023 | Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy. | 6 |
| 37720188 | 2023 | LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17. | 1 |
| 38140584 | 2023 | PDIA4 Is a Host Factor Important for Lymphocytic Choriomeningitis Virus Infection. | 0 |
| 35460376 | 2022 | Circulating protein disulfide isomerase family member 4 is associated with type 2 diabetes mellitus, insulin sensitivity, and obesity. | 2 |
Citation
Dessen P
PDIA4 (protein disulfide isomerase family A member 4)
Atlas Genet Cytogenet Oncol Haematol. 2012-01-01
Online version: http://atlasgeneticsoncology.org/gene/52569/pdia4
