Identity
HGNC
LOCATION
19q13.11
LOCUSID
ALIAS
ARX,HRIHFB2115,SAE2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10054
MIM: 613295
HGNC: 30661
Ensembl: ENSG00000126261
Variants:
dbSNP: 10054
ClinVar: 10054
TCGA: ENSG00000126261
COSMIC: UBA2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38682183 | 2024 | UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma. | 0 |
| 38682183 | 2024 | UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma. | 0 |
| 34467471 | 2022 | UBA2 promotes the progression of renal cell carcinoma by suppressing the p53 signaling. | 0 |
| 34467471 | 2022 | UBA2 promotes the progression of renal cell carcinoma by suppressing the p53 signaling. | 0 |
| 33979648 | 2021 | Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics. | 11 |
| 34040189 | 2021 | UBA2 variants underlie a recognizable syndrome with variable aplasia cutis congenita and ectrodactyly. | 5 |
| 34159400 | 2021 | Genome sequencing in families with congenital limb malformations. | 8 |
| 33979648 | 2021 | Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics. | 11 |
| 34040189 | 2021 | UBA2 variants underlie a recognizable syndrome with variable aplasia cutis congenita and ectrodactyly. | 5 |
| 34159400 | 2021 | Genome sequencing in families with congenital limb malformations. | 8 |
| 32938830 | 2020 | Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes. | 14 |
| 33008487 | 2020 | UBA2 activates Wnt/β-catenin signaling pathway during protection of R28 retinal precursor cells from hypoxia by extracellular vesicles derived from placental mesenchymal stem cells. | 7 |
| 32938830 | 2020 | Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes. | 14 |
| 33008487 | 2020 | UBA2 activates Wnt/β-catenin signaling pathway during protection of R28 retinal precursor cells from hypoxia by extracellular vesicles derived from placental mesenchymal stem cells. | 7 |
| 30848500 | 2019 | Identifying UBA2 as a proliferation and cell cycle regulator in lung cancer A549 cells. | 11 |
Citation
Dessen P
UBA2 (ubiquitin like modifier activating enzyme 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-02-01
Online version: http://atlasgeneticsoncology.org/gene/52587/uba2
