Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55323
MIM: 611300
HGNC: 24012
Ensembl: ENSG00000166173
Variants:
dbSNP: 55323
ClinVar: 55323
TCGA: ENSG00000166173
COSMIC: LARP6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166173 | ENST00000299213 | Q9BRS8 |
| ENSG00000166173 | ENST00000344870 | Q9BRS8 |
| ENSG00000166173 | ENST00000559140 | H0YMC6 |
| ENSG00000166173 | ENST00000559316 | K7EPD2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36691044 | 2023 | LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis. | 3 |
| 36691044 | 2023 | LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis. | 3 |
| 34896113 | 2022 | Characterization of Sequence-Specific Binding of LARP6 to the 5' Stem-Loop of Type I Collagen mRNAs and Implications for Rational Design of Antifibrotic Drugs. | 3 |
| 35176288 | 2022 | LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen. | 5 |
| 34896113 | 2022 | Characterization of Sequence-Specific Binding of LARP6 to the 5' Stem-Loop of Type I Collagen mRNAs and Implications for Rational Design of Antifibrotic Drugs. | 3 |
| 35176288 | 2022 | LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen. | 5 |
| 28112218 | 2017 | mTORC1 phosphorylates LARP6 to stimulate type I collagen expression. | 14 |
| 28782243 | 2017 | The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives. | 62 |
| 28112218 | 2017 | mTORC1 phosphorylates LARP6 to stimulate type I collagen expression. | 14 |
| 28782243 | 2017 | The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives. | 62 |
| 26932461 | 2016 | Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen. | 20 |
| 26932461 | 2016 | Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen. | 20 |
| 25488812 | 2015 | Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module. | 37 |
| 25488812 | 2015 | Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module. | 37 |
| 24469459 | 2014 | Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA. | 46 |
Citation
Dessen P
LARP6 (La ribonucleoprotein 6, translational regulator)
Atlas Genet Cytogenet Oncol Haematol. 2012-02-01
Online version: http://atlasgeneticsoncology.org/gene/52603/larp6
