IL17D (interleukin 17D)

2012-03-01  

Identity

HGNC
IL17D
LOCATION
13q12.11
LOCUSID
53342
ALIAS
IL-17D
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 53342
MIM: 607587
HGNC: 5984
Ensembl: ENSG00000172458

Variants:

dbSNP: 53342
ClinVar: 53342
TCGA: ENSG00000172458
COSMIC: IL17D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172458ENST00000304920Q8TAD2
ENSG00000172458ENST00000468605A0A087WWZ4
ENSG00000172458ENST00000498088A0A087WW17

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
Th17 cell differentiationKEGGko04659
Th17 cell differentiationKEGGhsa04659
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

References

Pubmed IDYearTitleCitations
377083352023Interleukin-17D produced by alveolar epithelial type II cells alleviates LPS-induced acute lung injury via the Nrf2 pathway.1
377083352023Interleukin-17D produced by alveolar epithelial type II cells alleviates LPS-induced acute lung injury via the Nrf2 pathway.1
359393362022Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway.5
359393362022Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway.5
340234352021Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D.3
340234352021Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D.3
286855462017Expression of inflammatory cytokines in ovarian epithelial cancer and their correlation.2
286855462017Expression of inflammatory cytokines in ovarian epithelial cancer and their correlation.2
275458892016Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.61
275458892016Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.61
247944412014Interleukin-17D mediates tumor rejection through recruitment of natural killer cells.49
247944412014Interleukin-17D mediates tumor rejection through recruitment of natural killer cells.49
234904202013The effects of IL-17 upon human natural killer cells.19
234904202013The effects of IL-17 upon human natural killer cells.19
221563482012IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes.50

Citation

Dessen P

IL17D (interleukin 17D)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52608/gene-fusions/js/lib/deep-insight-explorer/