Identity
HGNC
LOCATION
10q22.3
LOCUSID
ALIAS
MAT,MATA1,SAMS,SAMS1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4143
MIM: 610550
HGNC: 6903
Ensembl: ENSG00000151224
Variants:
dbSNP: 4143
ClinVar: 4143
TCGA: ENSG00000151224
COSMIC: MAT1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000151224 | ENST00000372213 | Q00266 |
| ENSG00000151224 | ENST00000455001 | B1ANE6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38086446 | 2024 | Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis. | 1 |
| 38086446 | 2024 | Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis. | 1 |
| 35008908 | 2022 | Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis. | 5 |
| 35091576 | 2022 | Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. | 8 |
| 35008908 | 2022 | Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis. | 5 |
| 35091576 | 2022 | Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease. | 8 |
| 32080887 | 2020 | Reciprocal Regulation Between Forkhead Box M1/NF-κB and Methionine Adenosyltransferase 1A Drives Liver Cancer. | 23 |
| 32335878 | 2020 | [Newborn screening and variant analysis for methionine adenosyltransferase I/III deficiency]. | 0 |
| 32496220 | 2020 | Structural basis of the dominant inheritance of hypermethioninemia associated with the Arg264His mutation in the MAT1A gene. | 3 |
| 32980525 | 2020 | Methionine adenosyltransferase I/III deficiency: Long-term follow-up and treatment of 3 adult siblings. | 0 |
| 32080887 | 2020 | Reciprocal Regulation Between Forkhead Box M1/NF-κB and Methionine Adenosyltransferase 1A Drives Liver Cancer. | 23 |
| 32335878 | 2020 | [Newborn screening and variant analysis for methionine adenosyltransferase I/III deficiency]. | 0 |
| 32496220 | 2020 | Structural basis of the dominant inheritance of hypermethioninemia associated with the Arg264His mutation in the MAT1A gene. | 3 |
| 32980525 | 2020 | Methionine adenosyltransferase I/III deficiency: Long-term follow-up and treatment of 3 adult siblings. | 0 |
| 31600961 | 2019 | Methionine Adenosyltransferase 1a (MAT1A) Enhances Cell Survival During Chemotherapy Treatment and is Associated with Drug Resistance in Bladder Cancer PDX Mice. | 6 |
Citation
Dessen P
MAT1A (methionine adenosyltransferase 1A)
Atlas Genet Cytogenet Oncol Haematol. 2012-03-01
Online version: http://atlasgeneticsoncology.org/gene/52635/mat1a
