SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor)

2012-03-01  

Identity

HGNC
LOCATION
3p13
LOCUSID
ALIAS
GRIM-1,Shq1p

Other Information

Locus ID:

NCBI: 55164
MIM: 613663
HGNC: 25543
Ensembl: ENSG00000144736

Variants:

dbSNP: 55164
ClinVar: 55164
TCGA: ENSG00000144736
COSMIC: SHQ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144736ENST00000325599Q6PI26
ENSG00000144736ENST00000444040F8WDZ9
ENSG00000144736ENST00000463369Q6PI26
ENSG00000144736ENST00000471526F8WBC6
ENSG00000144736ENST00000482785C9J6N3

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368478452023Biallelic SHQ1 variants in early infantile hypotonia and paroxysmal dystonia as the leading manifestation.3
368478452023Biallelic SHQ1 variants in early infantile hypotonia and paroxysmal dystonia as the leading manifestation.3
345421572022Compound heterozygous variants in SHQ1 are associated with a spectrum of neurological features, including early-onset dystonia.4
345421572022Compound heterozygous variants in SHQ1 are associated with a spectrum of neurological features, including early-onset dystonia.4
325229792020SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.4
325229792020SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.4
303231922018SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival.21
303231922018SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival.21
255538442015Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.8
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.25
255538442015Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.8
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.25
250815412014Reversed expression of GRIM-1 and GRP78 in human non-small cell lung cancer.6
250815412014Reversed expression of GRIM-1 and GRP78 in human non-small cell lung cancer.6
219316442011GRIM-1, a novel growth suppressor, inhibits rRNA maturation by suppressing small nucleolar RNAs.7

Citation

Dessen P

SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52641/shq1