NOB1 (NIN1 (RPN12) binding protein 1 homolog)

2012-03-01 Affiliation

Identity

HGNC

NOB1

LOCATION

16q22.1

LOCUSID

28987

ALIAS

ART-4,MST158,MSTP158,NOB1P,PSMD8BP1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 28987
MIM: 613586
HGNC: 29540
Ensembl: ENSG00000141101

Variants:

dbSNP: 28987
ClinVar: 28987
TCGA: ENSG00000141101
COSMIC: NOB1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000141101	ENST00000268802	Q9ULX3
ENSG00000141101	ENST00000564620	H3BUR4
ENSG00000141101	ENST00000569871	H3BUR4

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Ribosome biogenesis in eukaryotes	KEGG	ko03008
Ribosome biogenesis in eukaryotes	KEGG	hsa03008
Gene Expression	REACTOME	R-HSA-74160
rRNA processing	REACTOME	R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol	REACTOME	R-HSA-6791226
rRNA processing in the nucleus and cytosol	REACTOME	R-HSA-8868773

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
31906747	2021	Silencing NOB1 Can Affect Cell Proliferation and Apoptosis Via the C-Jun N-Terminal Kinase Pathway in Colorectal Cancer.	3
34530115	2021	LncRNA FEZF1-AS1 aggravates cell proliferation and migration in glioblastoma.	1
31906747	2021	Silencing NOB1 Can Affect Cell Proliferation and Apoptosis Via the C-Jun N-Terminal Kinase Pathway in Colorectal Cancer.	3
34530115	2021	LncRNA FEZF1-AS1 aggravates cell proliferation and migration in glioblastoma.	1
32357945	2020	MiR-363 suppresses cell migration, invasion, and epithelial-mesenchymal transition of osteosarcoma by binding to NOB1.	8
32357945	2020	MiR-363 suppresses cell migration, invasion, and epithelial-mesenchymal transition of osteosarcoma by binding to NOB1.	8
30854959	2019	NOB1: A Potential Biomarker or Target in Cancer.	4
31173298	2019	MicroRNA-139-3p suppresses growth and metastasis of glioblastoma via inhibition of NIN1/RPNI2 binding protein 1 homolog.	11
30854959	2019	NOB1: A Potential Biomarker or Target in Cancer.	4
31173298	2019	MicroRNA-139-3p suppresses growth and metastasis of glioblastoma via inhibition of NIN1/RPNI2 binding protein 1 homolog.	11
29115574	2018	Long non-coding RNA SNHG1 regulates NOB1 expression by sponging miR-326 and promotes tumorigenesis in osteosarcoma.	63
29749434	2018	miR‑145 inhibits human non‑small-cell lung cancer growth by dual-targeting RIOK2 and NOB1.	16
30176151	2018	Domain definition and interaction mapping for the endonuclease complex hNob1/hPno1.	5
30274015	2018	NOB1 Gene as a Potential Biomarker in Clinical Outcomes and Prognosis of Patients with Gastric Cancer.	4
29115574	2018	Long non-coding RNA SNHG1 regulates NOB1 expression by sponging miR-326 and promotes tumorigenesis in osteosarcoma.	63

Citation

Dessen P

NOB1 (NIN1 (RPN12) binding protein 1 homolog)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52654