Identity
HGNC
LOCATION
14q21.1
LOCUSID
ALIAS
C14orf27,CEG1,EGFR-5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 161198
MIM: 616845
HGNC: 19832
Ensembl: ENSG00000176435
Variants:
dbSNP: 161198
ClinVar: 161198
TCGA: ENSG00000176435
COSMIC: CLEC14A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176435 | ENST00000342213 | Q86T13 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35576868 | 2022 | CLEC14A was up-regulated in hepatocellular carcinoma and may function as a potential diagnostic biomarker. | 2 |
| 35576868 | 2022 | CLEC14A was up-regulated in hepatocellular carcinoma and may function as a potential diagnostic biomarker. | 2 |
| 31964714 | 2020 | Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein. | 10 |
| 32696621 | 2020 | An evaluation of the tumour endothelial marker CLEC14A as a therapeutic target in solid tumours. | 9 |
| 31964714 | 2020 | Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein. | 10 |
| 32696621 | 2020 | An evaluation of the tumour endothelial marker CLEC14A as a therapeutic target in solid tumours. | 9 |
| 30132150 | 2019 | Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer. | 19 |
| 30191970 | 2019 | Methylation of CLEC14A is associated with its expression and lung adenocarcinoma progression. | 8 |
| 31852888 | 2019 | Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7. | 21 |
| 30132150 | 2019 | Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer. | 19 |
| 30191970 | 2019 | Methylation of CLEC14A is associated with its expression and lung adenocarcinoma progression. | 8 |
| 31852888 | 2019 | Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7. | 21 |
| 28671670 | 2017 | Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface. | 38 |
| 28671670 | 2017 | Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface. | 38 |
| 25745997 | 2015 | Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth. | 29 |
Citation
Dessen P
CLEC14A (C-type lectin domain containing 14A)
Atlas Genet Cytogenet Oncol Haematol. 2012-04-01
Online version: http://atlasgeneticsoncology.org/gene/52670/clec14a
