Identity
HGNC
LOCATION
Xp11.3
LOCUSID
ALIAS
MRX108,NHE-7,NHE7,SLC9A6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84679
MIM: 300368
HGNC: 17123
Ensembl: ENSG00000065923
Variants:
dbSNP: 84679
ClinVar: 84679
TCGA: ENSG00000065923
COSMIC: SLC9A7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000065923 | ENST00000328306 | Q96T83 |
| ENSG00000065923 | ENST00000328306 | A0A024R176 |
| ENSG00000065923 | ENST00000616978 | A0A087WXD1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38152992 | 2024 | NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma. | 2 |
| 38152992 | 2024 | NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma. | 2 |
| 30335141 | 2019 | A recurrent missense variant in SLC9A7 causes nonsyndromic X-linked intellectual disability with alteration of Golgi acidification and aberrant glycosylation. | 12 |
| 30335141 | 2019 | A recurrent missense variant in SLC9A7 causes nonsyndromic X-linked intellectual disability with alteration of Golgi acidification and aberrant glycosylation. | 12 |
| 28166740 | 2017 | Delineation of cystinuria in Saudi Arabia: A case series. | 3 |
| 28166740 | 2017 | Delineation of cystinuria in Saudi Arabia: A case series. | 3 |
| 24767989 | 2014 | The intracellular Na(+)/H(+) exchanger NHE7 effects a Na(+)-coupled, but not K(+)-coupled proton-loading mechanism in endocytosis. | 20 |
| 24767989 | 2014 | The intracellular Na(+)/H(+) exchanger NHE7 effects a Na(+)-coupled, but not K(+)-coupled proton-loading mechanism in endocytosis. | 20 |
| 22076128 | 2012 | Organellar (Na+, K+)/H+ exchanger NHE7 regulates cell adhesion, invasion and anchorage-independent growth of breast cancer MDA-MB-231 cells. | 12 |
| 22076128 | 2012 | Organellar (Na+, K+)/H+ exchanger NHE7 regulates cell adhesion, invasion and anchorage-independent growth of breast cancer MDA-MB-231 cells. | 12 |
| 21171650 | 2011 | Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions. | 45 |
| 21171650 | 2011 | Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions. | 45 |
| 20364249 | 2010 | A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes. | 9 |
| 20364249 | 2010 | A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes. | 9 |
| 18654930 | 2008 | Identification and biochemical characterization of the SLC9A7 interactome. | 9 |
Citation
Dessen P
SLC9A7 (solute carrier family 9 member A7)
Atlas Genet Cytogenet Oncol Haematol. 2012-04-01
Online version: http://atlasgeneticsoncology.org/gene/52687/slc9a7
