RNF180 (ring finger protein 180)

2012-04-01  

Identity

HGNC
LOCATION
5q12.3
LOCUSID
ALIAS
RINES
FUSION GENES

Other Information

Locus ID:

NCBI: 285671
MIM: 616015
HGNC: 27752
Ensembl: ENSG00000164197

Variants:

dbSNP: 285671
ClinVar: 285671
TCGA: ENSG00000164197
COSMIC: RNF180

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164197ENST00000296615Q86T96
ENSG00000164197ENST00000389100Q86T96
ENSG00000164197ENST00000504296D6RE88

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371477332023E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1.4
371477332023E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1.4
339315792021DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells.14
339315792021DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells.14
330823252020RNF180 mediates STAT3 activity by regulating the expression of RhoC via the proteasomal pathway in gastric cancer cells.17
330823252020RNF180 mediates STAT3 activity by regulating the expression of RhoC via the proteasomal pathway in gastric cancer cells.17
268055522016Clinical and experimental role of ring finger protein 180 on lymph node metastasis and survival in gastric cancer.15
270501492016Promoter methylation of RNF180 is associated with H.pylori infection and serves as a marker for gastric cancer and atrophic gastritis.12
272232572016Mediation of the malignant biological characteristics of gastric cancer cells by the methylated CpG islands in RNF180 DNA promoter.5
268055522016Clinical and experimental role of ring finger protein 180 on lymph node metastasis and survival in gastric cancer.15
270501492016Promoter methylation of RNF180 is associated with H.pylori infection and serves as a marker for gastric cancer and atrophic gastritis.12
272232572016Mediation of the malignant biological characteristics of gastric cancer cells by the methylated CpG islands in RNF180 DNA promoter.5
257694512015Evaluating the clinical feasibility: The direct bisulfite genomic sequencing for examination of methylated status of E3 ubiquitin ligase RNF180 DNA promoter to predict the survival of gastric cancer.9
257694512015Evaluating the clinical feasibility: The direct bisulfite genomic sequencing for examination of methylated status of E3 ubiquitin ligase RNF180 DNA promoter to predict the survival of gastric cancer.9
248334022014Methylation of CpG sites in RNF180 DNA promoter prediction poor survival of gastric cancer.14

Citation

Dessen P

RNF180 (ring finger protein 180)

Atlas Genet Cytogenet Oncol Haematol. 2012-04-01

Online version: http://atlasgeneticsoncology.org/gene/52691/css/js/lib/zoomerang.js