ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)

2012-06-01 Affiliation

Identity

HGNC

ACAP1

LOCATION

17p13.1

LOCUSID

9744

ALIAS

CENTB1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9744
MIM: 607763
HGNC: 16467
Ensembl: ENSG00000072818

Variants:

dbSNP: 9744
ClinVar: 9744
TCGA: ENSG00000072818
COSMIC: ACAP1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000072818	ENST00000158762	Q15027
ENSG00000072818	ENST00000570457	I3L0K9
ENSG00000072818	ENST00000575425	I3L268

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Endocytosis	KEGG	ko04144
Endocytosis	KEGG	hsa04144

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
32456571	2020	Expression of ACAP1 Is Associated with Tumor Immune Infiltration and Clinical Outcome of Ovarian Cancer.	11
32456571	2020	Expression of ACAP1 Is Associated with Tumor Immune Infiltration and Clinical Outcome of Ovarian Cancer.	11
31291238	2019	ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages.	1
31291238	2019	ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages.	1
25502766	2015	Translational study of Alzheimer's disease (AD) biomarkers from brain tissues in AβPP/PS1 mice and serum of AD patients.	25
25502766	2015	Translational study of Alzheimer's disease (AD) biomarkers from brain tissues in AβPP/PS1 mice and serum of AD patients.	25
25225293	2014	The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5β1 traffic.	30
25225293	2014	The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5β1 traffic.	30
23317930	2013	Gene and protein expression of centaurin beta 1 (CENTB1) are up-regulated in patients with ulcerative colitis.	1
23317930	2013	Gene and protein expression of centaurin beta 1 (CENTB1) are up-regulated in patients with ulcerative colitis.	1
22188517	2012	The oncogenic TBC domain protein USP6/TRE17 regulates cell migration and cytokinesis.	10
22645133	2012	Mechanistic insights into regulated cargo binding by ACAP1 protein.	13
22188517	2012	The oncogenic TBC domain protein USP6/TRE17 regulates cell migration and cytokinesis.	10
22645133	2012	Mechanistic insights into regulated cargo binding by ACAP1 protein.	13
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78

Citation

Dessen P

ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-06-01

Online version: http://atlasgeneticsoncology.org/gene/52747