FOCAD (focadhesin)

2012-06-01  

Identity

HGNC
FOCAD
LOCATION
9p21.3
LOCUSID
54914
ALIAS
KIAA1797
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54914
MIM: 614606
HGNC: 23377
Ensembl: ENSG00000188352

Variants:

dbSNP: 54914
ClinVar: 54914
TCGA: ENSG00000188352
COSMIC: FOCAD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188352ENST00000338382Q5VW36
ENSG00000188352ENST00000380249Q5VW36
ENSG00000188352ENST00000603044S4R450
ENSG00000188352ENST00000603648S4R437
ENSG00000188352ENST00000603695S4R3S9
ENSG00000188352ENST00000604254S4R3N8
ENSG00000188352ENST00000605086S4R400

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377309642024Exosomal circKIAA1797 Regulates Cell Progression and Glycolysis by Targeting miR-4429/PBX3 Pathway in Gastric Cancer.0
377309642024Exosomal circKIAA1797 Regulates Cell Progression and Glycolysis by Targeting miR-4429/PBX3 Pathway in Gastric Cancer.0
356220752022FOCAD Indel in a Family With Juvenile Polyposis Syndrome.0
358641902022Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis.5
356220752022FOCAD Indel in a Family With Juvenile Polyposis Syndrome.0
358641902022Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis.5
314737902020FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.11
314737902020FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.11
268565372016Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication.13
268565372016Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication.13
257121962015Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development.13
257121962015Germline deletions in the tumour suppressor gene FOCAD are associated with polyposis and colorectal cancer development.13
224273312012KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.23
224273312012KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.23
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

FOCAD (focadhesin)

Atlas Genet Cytogenet Oncol Haematol. 2012-06-01

Online version: http://atlasgeneticsoncology.org/gene/52756