Identity
HGNC
LOCATION
Xp22.2
LOCUSID
ALIAS
U2AF1-RS2,U2AF1L2,U2AF1RS2,URP,ZC3H22
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8233
MIM: 300028
HGNC: 23019
Ensembl: ENSG00000169249
Variants:
dbSNP: 8233
ClinVar: 8233
TCGA: ENSG00000169249
COSMIC: ZRSR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169249 | ENST00000307771 | Q15696 |
| ENSG00000169249 | ENST00000380308 | A6NDW0 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38088204 | 2024 | Global analysis of binding sites of U2AF1 and ZRSR2 reveals RNA elements required for mutually exclusive splicing by the U2- and U12-type spliceosome. | 0 |
| 38158857 | 2024 | Differential alternative splicing analysis links variation in ZRSR2 to a novel type of oral-facial-digital syndrome. | 0 |
| 38088204 | 2024 | Global analysis of binding sites of U2AF1 and ZRSR2 reveals RNA elements required for mutually exclusive splicing by the U2- and U12-type spliceosome. | 0 |
| 38158857 | 2024 | Differential alternative splicing analysis links variation in ZRSR2 to a novel type of oral-facial-digital syndrome. | 0 |
| 34615655 | 2022 | Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis. | 36 |
| 34615655 | 2022 | Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis. | 36 |
| 33568749 | 2021 | ZRSR2 overexpression is a frequent and early event in castration-resistant prostate cancer development. | 0 |
| 33568749 | 2021 | ZRSR2 overexpression is a frequent and early event in castration-resistant prostate cancer development. | 0 |
| 31124956 | 2019 | Effect of RNA splicing machinery gene mutations on prognosis of patients with MDS: A meta-analysis. | 5 |
| 31361176 | 2019 | ZRSR2 mutation in a child with refractory macrocytic anemia and Down Syndrome. | 1 |
| 31124956 | 2019 | Effect of RNA splicing machinery gene mutations on prognosis of patients with MDS: A meta-analysis. | 5 |
| 31361176 | 2019 | ZRSR2 mutation in a child with refractory macrocytic anemia and Down Syndrome. | 1 |
| 28942350 | 2017 | Refractory macrocytic anemias in patients with clonal hematopoietic disorders and isolated mutations of the spliceosome gene ZRSR2. | 6 |
| 28942350 | 2017 | Refractory macrocytic anemias in patients with clonal hematopoietic disorders and isolated mutations of the spliceosome gene ZRSR2. | 6 |
| 25586593 | 2015 | Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome. | 113 |
Citation
Dessen P
ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-06-01
Online version: http://atlasgeneticsoncology.org/gene/52759/zrsr2
