Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5833
MIM: 602679
HGNC: 8756
Ensembl: ENSG00000185813
Variants:
dbSNP: 5833
ClinVar: 5833
TCGA: ENSG00000185813
COSMIC: PCYT2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450163 | lamivudine | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31577958 | 2019 | Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. | 23 |
| 31637422 | 2019 | Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia. | 47 |
| 31577958 | 2019 | Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. | 23 |
| 31637422 | 2019 | Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia. | 47 |
| 24519946 | 2014 | Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation. | 10 |
| 24802409 | 2014 | Human CTP:phosphoethanolamine cytidylyltransferase: enzymatic properties and unequal catalytic roles of CTP-binding motifs in two cytidylyltransferase domains. | 6 |
| 24519946 | 2014 | Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation. | 10 |
| 24802409 | 2014 | Human CTP:phosphoethanolamine cytidylyltransferase: enzymatic properties and unequal catalytic roles of CTP-binding motifs in two cytidylyltransferase domains. | 6 |
| 22339418 | 2012 | Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP:ethanolaminephosphate cytidylyltransferase-Pcyt2 activity. | 20 |
| 22339418 | 2012 | Breast cancer cells adapt to metabolic stress by increasing ethanolamine phospholipid synthesis and CTP:ethanolaminephosphate cytidylyltransferase-Pcyt2 activity. | 20 |
| 18583706 | 2008 | Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1. | 16 |
| 18583706 | 2008 | Stimulation of the human CTP:phosphoethanolamine cytidylyltransferase gene by early growth response protein 1. | 16 |
| 16023412 | 2005 | Characterization of transcription factors and cis-acting elements that regulate human CTP: phosphoethanolamine cytidylyltransferase (Pcyt2). | 4 |
| 16023412 | 2005 | Characterization of transcription factors and cis-acting elements that regulate human CTP: phosphoethanolamine cytidylyltransferase (Pcyt2). | 4 |
Citation
Dessen P
PCYT2 (phosphate cytidylyltransferase 2, ethanolamine)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52792/pcyt2
