CACTIN (cactin, spliceosome C complex subunit)

2012-08-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
C19orf29,NY-REN-24,fSAPc
FUSION GENES

Other Information

Locus ID:

NCBI: 58509
MIM: 618536
HGNC: 29938
Ensembl: ENSG00000105298

Variants:

dbSNP: 58509
ClinVar: 58509
TCGA: ENSG00000105298
COSMIC: CACTIN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105298ENST00000221899Q8WUQ7
ENSG00000105298ENST00000248420Q8WUQ7
ENSG00000105298ENST00000429344Q8WUQ7
ENSG00000105298ENST00000585942Q8WUQ7
ENSG00000105298ENST00000588749K7EQE3
ENSG00000105298ENST00000589321K7EMQ0
ENSG00000105298ENST00000591726K7EIU6
ENSG00000105298ENST00000592721K7ENY9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
280628512017Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.12
280628512017Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.12
263635542016TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin.25
263635542016TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin.25
260331102015Possible role of cortactin phosphorylation by protein kinase Cα in actin-bundle formation at growth cone.3
260331102015Possible role of cortactin phosphorylation by protein kinase Cα in actin-bundle formation at growth cone.3
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

CACTIN (cactin, spliceosome C complex subunit)

Atlas Genet Cytogenet Oncol Haematol. 2012-08-01

Online version: http://atlasgeneticsoncology.org/gene/52793/tumors-explorer/tumors-explorer/gene-fusions/?id=52793