FERMT1 (FERM domain containing kindlin 1)

2010-03-01  

Identity

HGNC
FERMT1
LOCATION
20p12.3
LOCUSID
55612
ALIAS
C20orf42,DTGCU2,KIND1,UNC112A,URP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55612
MIM: 607900
HGNC: 15889
Ensembl: ENSG00000101311

Variants:

dbSNP: 55612
ClinVar: 55612
TCGA: ENSG00000101311
COSMIC: FERMT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101311ENST00000217289Q9BQL6
ENSG00000101311ENST00000378844Q5JWV4
ENSG00000101311ENST00000536936G3V1L6

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382004432024FERMT1 promotes cell migration and invasion in non-small cell lung cancer via regulating PKP3-mediated activation of p38 MAPK signaling.0
382004432024FERMT1 promotes cell migration and invasion in non-small cell lung cancer via regulating PKP3-mediated activation of p38 MAPK signaling.0
369810052023FERMT1 Is a Prognostic Marker Involved in Immune Infiltration of Pancreatic Adenocarcinoma Correlating with m(6)A Modification and Necroptosis.1
369810052023FERMT1 Is a Prognostic Marker Involved in Immune Infiltration of Pancreatic Adenocarcinoma Correlating with m(6)A Modification and Necroptosis.1
351891502022Characterization of Amino Acid Substitutions and Deletions in Kindlin-1 FERM Domain: Relevance for Precision Medicine.0
354521912022Kindlin-1 modulates the EGFR pathway and predicts sensitivity to EGFR inhibitors across cancer types.0
351891502022Characterization of Amino Acid Substitutions and Deletions in Kindlin-1 FERM Domain: Relevance for Precision Medicine.0
354521912022Kindlin-1 modulates the EGFR pathway and predicts sensitivity to EGFR inhibitors across cancer types.0
336834372021Examination of FERMT1 expression in placental chorionic villi and its role in HTR8-SVneo cell invasion.2
340352802021Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions.17
348149152021FERMT1 knockdown inhibits oral squamous cell carcinoma cell epithelial-mesenchymal transition by inactivating the PI3K/AKT signaling pathway.8
336834372021Examination of FERMT1 expression in placental chorionic villi and its role in HTR8-SVneo cell invasion.2
340352802021Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions.17
348149152021FERMT1 knockdown inhibits oral squamous cell carcinoma cell epithelial-mesenchymal transition by inactivating the PI3K/AKT signaling pathway.8
319579002020A novel pathogenic FERMT1 variant in four families with Kindler syndrome in Argentina.2

Citation

Dessen P

FERMT1 (FERM domain containing kindlin 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/52820/gene-fusions/js/lib/css/template-nav.css