Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116844
MIM: 611289
HGNC: 29480
Ensembl: ENSG00000171236
Variants:
dbSNP: 116844
ClinVar: 116844
TCGA: ENSG00000171236
COSMIC: LRG1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171236 | ENST00000306390 | P02750 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38246328 | 2024 | Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway. | 1 |
| 38380988 | 2024 | Relation between LRG1 and CD4(+) T cells, cognitive impairment and neurological function in patients with acute ischemic stroke. | 1 |
| 38413424 | 2024 | High serum levels of leucine-rich α-2 glycoprotein 1 (LRG-1) are associated with poor survival in patients with early breast cancer. | 1 |
| 38898137 | 2024 | LRG1 and SDR16C5 protein expressions differ according to HPV status in oropharyngeal squamous cell carcinoma. | 0 |
| 38246328 | 2024 | Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway. | 1 |
| 38380988 | 2024 | Relation between LRG1 and CD4(+) T cells, cognitive impairment and neurological function in patients with acute ischemic stroke. | 1 |
| 38413424 | 2024 | High serum levels of leucine-rich α-2 glycoprotein 1 (LRG-1) are associated with poor survival in patients with early breast cancer. | 1 |
| 38898137 | 2024 | LRG1 and SDR16C5 protein expressions differ according to HPV status in oropharyngeal squamous cell carcinoma. | 0 |
| 36334015 | 2023 | Leucine-Rich Alpha-2 Glycoprotein Is a Reliable Serum Biomarker for Evaluating Clinical and Endoscopic Disease Activity in Inflammatory Bowel Disease. | 7 |
| 36516193 | 2023 | Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes. | 5 |
| 36577901 | 2023 | Leucine-Rich Alpha-2-Glycoprotein 1 is a Systemic Biomarker of Early Brain Injury and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage. | 2 |
| 36608792 | 2023 | Predictive Value of Leucine-Rich Alpha-2 Glycoprotein 1 in Cerebrospinal Fluid for the Prognosis of Aneurysmal Subarachnoid Hemorrhage: A Prospective Study. | 0 |
| 36880154 | 2023 | Serum leucine-rich alpha-2 glycoprotein and calprotectin in children with inflammatory bowel disease: A multicenter study in Japan. | 2 |
| 37047015 | 2023 | Diagnostic Accuracy of Leucine-Rich α-2-Glycoprotein 1 as a Non-Invasive Salivary Biomarker in Pediatric Appendicitis. | 7 |
| 37089863 | 2023 | Systemic LRG1 Expression in Melanoma is Associated with Disease Progression and Recurrence. | 3 |
Citation
Dessen P
LRG1 (leucine rich alpha-2-glycoprotein 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52827/lrg1
