Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3955
MIM: 602576
HGNC: 6560
Ensembl: ENSG00000106003
Variants:
dbSNP: 3955
ClinVar: 3955
TCGA: ENSG00000106003
COSMIC: LFNG
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37038048 | 2023 | Identification of bi-allelic LFNG variants in three patients and further clinical and molecular refinement of spondylocostal dysostosis 3. | 0 |
| 37038048 | 2023 | Identification of bi-allelic LFNG variants in three patients and further clinical and molecular refinement of spondylocostal dysostosis 3. | 0 |
| 33562410 | 2021 | Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers. | 7 |
| 33894418 | 2021 | Lunatic fringe promotes the aggregation of CADASIL NOTCH3 mutant proteins. | 1 |
| 33562410 | 2021 | Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers. | 7 |
| 33894418 | 2021 | Lunatic fringe promotes the aggregation of CADASIL NOTCH3 mutant proteins. | 1 |
| 30531807 | 2019 | Identification of novel LFNG mutations in spondylocostal dysostosis. | 4 |
| 30531807 | 2019 | Identification of novel LFNG mutations in spondylocostal dysostosis. | 4 |
| 29193607 | 2018 | Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis. | 13 |
| 29193607 | 2018 | Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis. | 13 |
| 28938159 | 2017 | Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer. | 8 |
| 28938159 | 2017 | Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer. | 8 |
| 26279302 | 2016 | Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer. | 19 |
| 27156840 | 2016 | Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1. | 8 |
| 26279302 | 2016 | Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer. | 19 |
Citation
Dessen P
LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52840/lfng
