Identity
HGNC
LOCATION
11p13
LOCUSID
ALIAS
APIP2,CGI-29,CGI29,MMRP19,hAPIP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51074
MIM: 612491
HGNC: 17581
Ensembl: ENSG00000149089
Variants:
dbSNP: 51074
ClinVar: 51074
TCGA: ENSG00000149089
COSMIC: APIP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000149089 | ENST00000395787 | Q96GX9 |
| ENSG00000149089 | ENST00000532428 | S4R3D6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38423248 | 2024 | APIP regulated by YAP propels methionine cycle and metastasis in head and neck squamous cell carcinoma. | 0 |
| 38423248 | 2024 | APIP regulated by YAP propels methionine cycle and metastasis in head and neck squamous cell carcinoma. | 0 |
| 31263105 | 2019 | Cardioprotective role of APIP in myocardial infarction through ADORA2B. | 5 |
| 31263105 | 2019 | Cardioprotective role of APIP in myocardial infarction through ADORA2B. | 5 |
| 26942872 | 2016 | APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis. | 6 |
| 26942872 | 2016 | APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis. | 6 |
| 24367089 | 2014 | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. | 20 |
| 24367089 | 2014 | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. | 20 |
| 22407486 | 2012 | Down-regulated expression of apoptosis-associated genes APIP and UACA in non-small cell lung carcinoma. | 15 |
| 22837397 | 2012 | Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. | 39 |
| 23192037 | 2012 | Crystallization and preliminary X-ray crystallographic analysis of human Apaf-1-interacting protein. | 1 |
| 23285211 | 2012 | Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathway. | 19 |
| 22407486 | 2012 | Down-regulated expression of apoptosis-associated genes APIP and UACA in non-small cell lung carcinoma. | 15 |
| 22837397 | 2012 | Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. | 39 |
| 23192037 | 2012 | Crystallization and preliminary X-ray crystallographic analysis of human Apaf-1-interacting protein. | 1 |
Citation
Dessen P
APIP (APAF1 interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52845/apip
