Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 940
MIM: 186760
HGNC: 1653
Ensembl: ENSG00000178562
Variants:
dbSNP: 940
ClinVar: 940
TCGA: ENSG00000178562
COSMIC: CD28
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000178562 | ENST00000324106 | P10747 |
| ENSG00000178562 | ENST00000374481 | P10747 |
| ENSG00000178562 | ENST00000458610 | P10747 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37069229 | 2023 | Recent advancements in the B7/CD28 immune checkpoint families: new biology and clinical therapeutic strategies. | 12 |
| 37108169 | 2023 | Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk. | 2 |
| 37168864 | 2023 | Kidney allograft rejection is associated with an imbalance of B cells, regulatory T cells and differentiated CD28-CD8+ T cells: analysis of a cohort of 1095 graft biopsies. | 0 |
| 37336986 | 2023 | c-Kit signaling potentiates CAR T cell efficacy in solid tumors by CD28- and IL-2-independent co-stimulation. | 4 |
| 37069229 | 2023 | Recent advancements in the B7/CD28 immune checkpoint families: new biology and clinical therapeutic strategies. | 12 |
| 37108169 | 2023 | Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk. | 2 |
| 37168864 | 2023 | Kidney allograft rejection is associated with an imbalance of B cells, regulatory T cells and differentiated CD28-CD8+ T cells: analysis of a cohort of 1095 graft biopsies. | 0 |
| 37336986 | 2023 | c-Kit signaling potentiates CAR T cell efficacy in solid tumors by CD28- and IL-2-independent co-stimulation. | 4 |
| 34738707 | 2022 | Clinicopathological significance of CD28 overexpression in adult T-cell leukemia/lymphoma. | 6 |
| 35003894 | 2022 | Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells. | 1 |
| 35553638 | 2022 | COPD is associated with increased pro-inflammatory CD28null CD8 T and NKT-like cells in the small airways. | 2 |
| 36131938 | 2022 | Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4(+) T cells. | 1 |
| 36476893 | 2022 | [Clinical Analysis of Pediatric Acute Leukemia Complicated with Septic Shock]. | 0 |
| 34738707 | 2022 | Clinicopathological significance of CD28 overexpression in adult T-cell leukemia/lymphoma. | 6 |
| 35003894 | 2022 | Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells. | 1 |
Citation
Dessen P
CD28 (CD28 molecule)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/52848/cd28
