Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57119
MIM: 609031
HGNC: 15932
Ensembl: ENSG00000101448
Variants:
dbSNP: 57119
ClinVar: 57119
TCGA: ENSG00000101448
COSMIC: EPPIN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101448 | ENST00000336443 | O95925 |
| ENSG00000101448 | ENST00000354280 | O95925 |
| ENSG00000101448 | ENST00000354280 | A0A384NYB9 |
| ENSG00000101448 | ENST00000409554 | B7ZBA9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Antimicrobial peptides | REACTOME | R-HSA-6803157 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28705940 | 2017 | Characterisation of eppin function: expression and activity in the lung. | 2 |
| 28705940 | 2017 | Characterisation of eppin function: expression and activity in the lung. | 2 |
| 24312623 | 2013 | Interacting proteins on human spermatozoa: adaptive evolution of the binding of semenogelin I to EPPIN. | 10 |
| 24358212 | 2013 | Correlation of epididymal protease inhibitor and fibronectin in human semen. | 3 |
| 24312623 | 2013 | Interacting proteins on human spermatozoa: adaptive evolution of the binding of semenogelin I to EPPIN. | 10 |
| 24358212 | 2013 | Correlation of epididymal protease inhibitor and fibronectin in human semen. | 3 |
| 22699487 | 2012 | Characterization of EPPIN's semenogelin I binding site: a contraceptive drug target. | 6 |
| 22699487 | 2012 | Characterization of EPPIN's semenogelin I binding site: a contraceptive drug target. | 6 |
| 21392882 | 2011 | Eppin expression in prostate cancer. | 2 |
| 21461566 | 2011 | Distribution of Eppin in mouse and human testis. | 1 |
| 21392882 | 2011 | Eppin expression in prostate cancer. | 2 |
| 21461566 | 2011 | Distribution of Eppin in mouse and human testis. | 1 |
| 19801569 | 2010 | The effect of anti-eppin antibodies on ionophore A23187-induced calcium influx and acrosome reaction of human spermatozoa. | 7 |
| 19889947 | 2010 | Analysis of recombinant human semenogelin as an inhibitor of human sperm motility. | 29 |
| 20158997 | 2010 | Variants in the Eppin gene show association with semen quality in Han-Chinese population. | 3 |
Citation
Dessen P
EPPIN (epididymal peptidase inhibitor)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52857/eppin
