Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25827
MIM: 605652
HGNC: 13598
Ensembl: ENSG00000153558
Variants:
dbSNP: 25827
ClinVar: 25827
TCGA: ENSG00000153558
COSMIC: FBXL2
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36460773 | 2023 | FBXL2 promotes E47 protein instability to inhibit breast cancer stemness and paclitaxel resistance. | 4 |
| 36460773 | 2023 | FBXL2 promotes E47 protein instability to inhibit breast cancer stemness and paclitaxel resistance. | 4 |
| 34635651 | 2021 | FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth. | 23 |
| 34635651 | 2021 | FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth. | 23 |
| 31679690 | 2020 | O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 to induce cancer progression. | 3 |
| 31953162 | 2020 | MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway. | 10 |
| 32205409 | 2020 | Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter. | 12 |
| 31679690 | 2020 | O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 to induce cancer progression. | 3 |
| 31953162 | 2020 | MiR-346-5p promotes colorectal cancer cell proliferation in vitro and in vivo by targeting FBXL2 and activating the β-catenin signaling pathway. | 10 |
| 32205409 | 2020 | Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter. | 12 |
| 28614300 | 2017 | PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth. | 106 |
| 28614300 | 2017 | PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth. | 106 |
| 26790640 | 2016 | F-box protein FBXL2 inhibits gastric cancer proliferation by ubiquitin-mediated degradation of forkhead box M1. | 18 |
| 26790640 | 2016 | F-box protein FBXL2 inhibits gastric cancer proliferation by ubiquitin-mediated degradation of forkhead box M1. | 18 |
| 26037928 | 2015 | Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase. | 103 |
Citation
Dessen P
FBXL2 (F-box and leucine rich repeat protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52859/fbxl2
