TOX4 (TOX high mobility group box family member 4)

2012-09-01  

Identity

HGNC
TOX4
LOCATION
14q11.2
LOCUSID
9878
ALIAS
C14orf92,KIAA0737,LCP1,MIG7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9878
MIM: 614032
HGNC: 20161
Ensembl: ENSG00000092203

Variants:

dbSNP: 9878
ClinVar: 9878
TCGA: ENSG00000092203
COSMIC: TOX4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092203ENST00000416256C9JNL1
ENSG00000092203ENST00000447695F8WCL8
ENSG00000092203ENST00000448790O94842
ENSG00000092203ENST00000455138F8WBE8
ENSG00000092203ENST00000455393F8WC04
ENSG00000092203ENST00000457430C9J919
ENSG00000092203ENST00000613569O94842

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377897772023Migration-inducing gene-7 promotes glioma cell proliferation and invasiveness via activating the MAPK signaling pathway.0
377897772023Migration-inducing gene-7 promotes glioma cell proliferation and invasiveness via activating the MAPK signaling pathway.0
349148932022TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver.9
353657352022TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells.6
349148932022TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver.9
353657352022TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells.6
243122782013TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.15
243122782013TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication.15
224968702012Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers.33
231274012012[Mig-7 enhances vasculogenic mimicry in gastric cancer cells].0
224968702012Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers.33
231274012012[Mig-7 enhances vasculogenic mimicry in gastric cancer cells].0
211847312011TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs.25
211847312011TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs.25
205160612010Identification and characterization of a novel human PP1 phosphatase complex.71

Citation

Dessen P

TOX4 (TOX high mobility group box family member 4)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52860/favicon/meetings/