MIRLET7B (microRNA let-7b)

2012-09-01  

Identity

HGNC
LOCATION
22q13.31
LOCUSID
ALIAS
LET7B,MIRNLET7B,hsa-let-7b,let-7b

Other Information

Locus ID:

NCBI: 406884
MIM: 611249
HGNC: 31479
Ensembl: ENSG00000284520
miRBase:

Variants:

dbSNP: 406884
ClinVar: 406884
TCGA: ENSG00000284520
COSMIC: MIRLET7B

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
387293262024Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.0
387293262024Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.0
364451202023Let-7b-5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1.4
365794682023Knockdown of let-7b in leukemia associated macrophages inhibit acute myeloid leukemia progression.0
366436462023Exosomes derived from M1 macrophages inhibit the proliferation of the A549 and H1299 lung cancer cell lines via the miRNA-let-7b-5p-GNG5 axis.6
369451262023Crohn's disease-associated AIEC inhibiting intestinal epithelial cell-derived exosomal let-7b expression regulates macrophage polarization to exacerbate intestinal fibrosis.5
371302712023PRB inhibited cell proliferation through let-7b-E2F1 in breast cancer.0
377110342023Serum‑derived exosomal hsa‑let‑7b‑5p as a biomarker for predicting the severity of coronary stenosis in patients with coronary heart disease and hyperglycemia.3
364451202023Let-7b-5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1.4
365794682023Knockdown of let-7b in leukemia associated macrophages inhibit acute myeloid leukemia progression.0
366436462023Exosomes derived from M1 macrophages inhibit the proliferation of the A549 and H1299 lung cancer cell lines via the miRNA-let-7b-5p-GNG5 axis.6
369451262023Crohn's disease-associated AIEC inhibiting intestinal epithelial cell-derived exosomal let-7b expression regulates macrophage polarization to exacerbate intestinal fibrosis.5
371302712023PRB inhibited cell proliferation through let-7b-E2F1 in breast cancer.0
377110342023Serum‑derived exosomal hsa‑let‑7b‑5p as a biomarker for predicting the severity of coronary stenosis in patients with coronary heart disease and hyperglycemia.3
348073762022MicroRNA let-7b inhibits hepatitis C virus and induces apoptosis in human hepatoma cells.1

Citation

Dessen P

MIRLET7B (microRNA let-7b)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52864/mirlet7b