MPPED2 (metallophosphoesterase domain containing 2)

2012-09-01  

Identity

HGNC
MPPED2
LOCATION
11p14.1
LOCUSID
744
ALIAS
239FB,C11orf8
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 744
MIM: 600911
HGNC: 1180
Ensembl: ENSG00000066382

Variants:

dbSNP: 744
ClinVar: 744
TCGA: ENSG00000066382
COSMIC: MPPED2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000066382ENST00000358117Q15777
ENSG00000066382ENST00000448418Q15777
ENSG00000066382ENST00000526437E9PQW8
ENSG00000066382ENST00000528686F2Z346

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
367973722023Association of MPPED2 gene variant rs10767873 with kidney function and risk of cardiovascular disease in patients with hypertension.0
367973722023Association of MPPED2 gene variant rs10767873 with kidney function and risk of cardiovascular disease in patients with hypertension.0
337340032021MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells.2
337340032021MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells.2
320402192020ACTN2 (rs6656267) and MPPED2 (rs11031093 and rs536007) polymorphisms in primary dentition caries: A case-control study.0
320402192020ACTN2 (rs6656267) and MPPED2 (rs11031093 and rs536007) polymorphisms in primary dentition caries: A case-control study.0
308460042019Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer.18
308460042019Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer.18
222621772012The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma.19
222621772012The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma.19
218244792011Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.8
218244792011Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.8
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94

Citation

Dessen P

MPPED2 (metallophosphoesterase domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52878