TRPA1 (transient receptor potential cation channel subfamily A member 1)

2012-09-01  

Identity

HGNC
LOCATION
8q21.11
LOCUSID
ALIAS
ANKTM1,FEPS,FEPS1

Other Information

Locus ID:

NCBI: 8989
MIM: 604775
HGNC: 497
Ensembl: ENSG00000104321

Variants:

dbSNP: 8989
ClinVar: 8989
TCGA: ENSG00000104321
COSMIC: TRPA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104321ENST00000262209O75762
ENSG00000104321ENST00000523582H0YAW0

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Inflammatory mediator regulation of TRP channelsKEGGhsa04750
Inflammatory mediator regulation of TRP channelsKEGGko04750
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351
TRP channelsREACTOMER-HSA-3295583

References

Pubmed IDYearTitleCitations
380726652024Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.1
385641622024NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells.0
386428922024Critical amino acid residues regulating TRPA1 Zn(2+) response: A comparative study across species.0
389634892024Human Transient Receptor Potential Ankyrin 1 Channel: Structure, Function, and Physiology.0
380726652024Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.1
385641622024NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells.0
386428922024Critical amino acid residues regulating TRPA1 Zn(2+) response: A comparative study across species.0
389634892024Human Transient Receptor Potential Ankyrin 1 Channel: Structure, Function, and Physiology.0
358714912023TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy.8
363715512023Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure.0
363788262023An Inhibitory Function of TRPA1 Channels in TGF-β1-driven Fibroblast-to-Myofibroblast Differentiation.4
364584522023Alkali cation-mediated topology displayed by an exonic G-rich sequence of TRPA1 gene.1
366348162023TRPA1 Mediates Contact Hypersensitivity Induced by 2,4-Dinitrochlorobenzene.0
368333382023Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review.1
368478172023Mechanisms and Consequences of Variable TRPA1 Expression by Airway Epithelial Cells: Effects of TRPV1 Genotype and Environmental Agonists on Cellular Responses to Pollutants in Vitro and Asthma.4

Citation

Dessen P

TRPA1 (transient receptor potential cation channel subfamily A member 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-09-01

Online version: http://atlasgeneticsoncology.org/gene/52884/trpa1