Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 345611
MIM: 608212
HGNC: 29597
Ensembl: ENSG00000237693
Variants:
dbSNP: 345611
ClinVar: 345611
TCGA: ENSG00000237693
COSMIC: IRGM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000237693 | ENST00000520549 | H0YBM2 |
| ENSG00000237693 | ENST00000522154 | A1A4Y4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Toxoplasmosis | KEGG | ko05145 |
| Toxoplasmosis | KEGG | hsa05145 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37993085 | 2024 | IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma. | 3 |
| 38514898 | 2024 | Impact of IRGM gene promoter polymorphisms on susceptibility to chronic HBV infection. | 0 |
| 37993085 | 2024 | IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma. | 3 |
| 38514898 | 2024 | Impact of IRGM gene promoter polymorphisms on susceptibility to chronic HBV infection. | 0 |
| 36580725 | 2023 | IRGM/Irgm1 deficiency inhibits neutrophil-platelet interactions and thrombosis in experimental atherosclerosis and arterial injury. | 1 |
| 36629440 | 2023 | Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice. | 8 |
| 36999177 | 2023 | Evaluation of Immunity-related GTPase Family M Protein (IRGM) SNPs among Egyptian Lupus Patients: A Case-control Study. | 0 |
| 37558924 | 2023 | Race-specific association of an IRGM risk allele with cytokine expression in human subjects. | 0 |
| 37705061 | 2023 | TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM. | 1 |
| 36580725 | 2023 | IRGM/Irgm1 deficiency inhibits neutrophil-platelet interactions and thrombosis in experimental atherosclerosis and arterial injury. | 1 |
| 36629440 | 2023 | Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice. | 8 |
| 36999177 | 2023 | Evaluation of Immunity-related GTPase Family M Protein (IRGM) SNPs among Egyptian Lupus Patients: A Case-control Study. | 0 |
| 37558924 | 2023 | Race-specific association of an IRGM risk allele with cytokine expression in human subjects. | 0 |
| 37705061 | 2023 | TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM. | 1 |
| 35661332 | 2022 | Association of IRGM gene promoter polymorphisms with hepatitis B virus infection. | 0 |
Citation
Dessen P
IRGM (immunity related GTPase M)
Atlas Genet Cytogenet Oncol Haematol. 2012-10-01
Online version: http://atlasgeneticsoncology.org/gene/52901/irgm
